Coen Donald M相关文献与解析，生知库 | 链接生命科学的每一步

Yu, Zishuo; Sathyanarayana, Pradeep; Liu, Cong; Tan, Joel M J; Yang, Pan; Das, Biswajit; Hu, Side; Fan, Xiaoyi; Ji, Chenggong; Weller, Sandra K; Shekhar, Mrinal; Coen, Donald M; Kranzusch, Philip J; Loparo, Joseph J; Abraham, Jonathan

发表日期：2026

文献求助收藏

Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1.

验证由诱导多能干细胞衍生的人类感觉神经元作为单纯疱疹病毒1型潜伏感染和再激活模型的有效性

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.01871-25

Oh Hyung Suk, Chou Shu-Fan, Raja Priya, Shim Jaehoon, Das Biswajit, Pesola Jean M, Romero NicolÃ¡s, Lee Jennifer S, Ng Alex, Buttermore Elizabeth D, Church George, Woolf Clifford J, Coen Donald M, Knipe David M

Regulation of the innate immune response in human neurons by ICP34.5 maintains herpes simplex virus 1 latency.

ICP34.5 对人类神经元中先天免疫反应的调节维持单纯疱疹病毒 1 型的潜伏状态。

期刊:

影响因子:

doi:10.1101/2025.04.04.647253

Canova Paige N, Katzenell Sarah, CerÃ³n Stacey, Charron Audra J, Pesola Jean M, Oh Hyung Suk, Coen Donald M, Knipe David M, Leib David A

Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.

病毒DNA聚合酶结构揭示了抗病毒药物耐药机制

期刊:Cell

影响因子:42.5

doi:10.1016/j.cell.2024.07.048

Shankar Sundaresh, Pan Junhua, Yang Pan, Bian Yuemin, OroszlÃ¡n GÃ¡bor, Yu Zishuo, Mukherjee Purba, Filman David J, Hogle James M, Shekhar Mrinal, Coen Donald M, Abraham Jonathan

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

孕妇接种疫苗可预防新生儿单纯疱疹病毒感染导致的死亡和行为疾病。

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.aau6039

Patel, Chaya D; Backes, Iara M; Taylor, Sean A; Jiang, Yike; Marchant, Arnaud; Pesola, Jean M; Coen, Donald M; Knipe, David M; Ackerman, Margaret E; Leib, David A

HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression

HSV-1 DNA聚合酶3'-5'外切酶缺陷突变体D368A表现出病毒DNA合成和聚合酶表达显著降低。

期刊:Journal of General Virology

影响因子:4.3

doi:10.1099/jgv.0.001138

Lawler, Jessica L; Coen, Donald M

微生物学

发表日期：2018

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Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site

单纯疱疹病毒1型DNA聚合酶RNase H活性以3'至5'方向发挥作用，并依赖于3'至5'外切酶活性位点。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.01813-17

Lawler, Jessica L; Mukherjee, Purba; Coen, Donald M

Getting to and through the inner nuclear membrane during herpesvirus nuclear egress

疱疹病毒核输出过程中到达并穿过核内膜的过程

期刊:Current Opinion in Cell Biology

影响因子:4.3

doi:10.1016/j.ceb.2016.12.007

Lye, Ming F; Wilkie, Adrian R; Filman, David J; Hogle, James M; Coen, Donald M

Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia

导致单纯疱疹病毒1型microRNA miR-H2失活的突变不会在感染的培养细胞或小鼠三叉神经节中显著增加ICP0基因的表达。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.02001-16

Pan, Dongli; Pesola, Jean M; Li, Gang; McCarron, Seamus; Coen, Donald M

Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase

环丙韦三磷酸酯对人巨细胞病毒DNA聚合酶的效力和立体选择性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00449-16

Chen, Han; Li, Chengwei; Zemlicka, Jiri; Gentry, Brian G; Bowlin, Terry L; Coen, Donald M

Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly

HSV-1解旋酶-引物酶抑制和复制叉复合物组装的机制

Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1.

验证由诱导多能干细胞衍生的人类感觉神经元作为单纯疱疹病毒1型潜伏感染和再激活模型的有效性

Regulation of the innate immune response in human neurons by ICP34.5 maintains herpes simplex virus 1 latency.

ICP34.5 对人类神经元中先天免疫反应的调节维持单纯疱疹病毒 1 型的潜伏状态。

Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.

病毒DNA聚合酶结构揭示了抗病毒药物耐药机制

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

孕妇接种疫苗可预防新生儿单纯疱疹病毒感染导致的死亡和行为疾病。

HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression

HSV-1 DNA聚合酶3'-5'外切酶缺陷突变体D368A表现出病毒DNA合成和聚合酶表达显著降低。

Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site

单纯疱疹病毒1型DNA聚合酶RNase H活性以3'至5'方向发挥作用，并依赖于3'至5'外切酶活性位点。

Getting to and through the inner nuclear membrane during herpesvirus nuclear egress

疱疹病毒核输出过程中到达并穿过核内膜的过程

Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia

导致单纯疱疹病毒1型microRNA miR-H2失活的突变不会在感染的培养细胞或小鼠三叉神经节中显著增加ICP0基因的表达。

Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase

环丙韦三磷酸酯对人巨细胞病毒DNA聚合酶的效力和立体选择性