A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance
一种基于酵母的全重组治疗性疫苗可在小鼠体内诱发 HBV X、S 和 Core 特异性 T 细胞,并激活人类 T 细胞识别与病毒清除相关的表位
期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0101904
Thomas H King, Charles B Kemmler, Zhimin Guo, Derrick Mann, Yingnian Lu, Claire Coeshott, Adam J Gehring, Antonio Bertoletti, Zi Z Ho, William Delaney, Anuj Gaggar, G Mani Subramanian, John G McHutchison, Shikha Shrivastava, Yu-Jin L Lee, Shyamasundaran Kottilil, Donald Bellgrau, Timothy Rodell, Dav