日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Results from an open-label phase 2a study of cerdulatinib, a dual spleen tyrosine kinase/janus kinase inhibitor, in relapsed/refractory peripheral T-cell lymphoma

一项开放标签的 2a 期研究结果显示,双重脾酪氨酸激酶/Janus 激酶抑制剂 cerdulatinib 可用于治疗复发/难治性外周 T 细胞淋巴瘤。

Horwitz, Steven M; Feldman, Tatyana A; Ye, Jing Christine; Khodadoust, Michael S; Munoz, Javier; Hamlin, Paul A; Kim, Youn H; Wilcox, Ryan A; Patel, Manish R; Coffey, Greg; Innes, Alison; Betz, Andreas; Holland, Jaymes; Guzman, Cristina B; Smith, Sonali M

Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma

塞度替尼是一种新型的双重SYK/JAK激酶抑制剂,对ABC型和GCB型弥漫性大B细胞淋巴瘤均具有广泛的抗肿瘤活性。

Ma, Jiao; Xing, Wei; Coffey, Greg; Dresser, Karen; Lu, Kellie; Guo, Ailin; Raca, Gordana; Pandey, Anjali; Conley, Pamela; Yu, Hongbo; Wang, Y Lynn

Methotrexate and a spleen tyrosine kinase inhibitor cooperate to inhibit responses to peripheral blood B cells in rheumatoid arthritis.

甲氨蝶呤和脾酪氨酸激酶抑制剂协同作用,抑制类风湿性关节炎患者外周血 B 细胞的反应

Coffey Greg, Betz Andreas, Graf Jonathan, Stephens Gillian, Hua Lin Pei, Imboden John, Sinha Uma