日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma

单次与重复静脉注射溶瘤呼肠孤病毒：对肝细胞癌免疫调节和合理化治疗方案安排的影响

期刊:International Journal of Cancer
影响因子:4.7
doi:10.1002/ijc.70386
Scott, Karen J; West, Emma J; Brownlie, Rebecca J; Ismail, Fay; Ralph, Christy; Heineman, Thomas; Coffey, Matt; Melcher, Alan A; Taylor, Alison; Papa, Salvatore; Samson, Adel
肿瘤
肿瘤免疫
微生物学
细胞生物学
免疫/内分泌
发表日期：2026
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Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects

蛋白酶体抑制剂可增强溶瘤呼肠孤病毒疗法在多发性骨髓瘤中的疗效，且该作用独立于其直接细胞毒性作用。

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-024-01645-3
Dona, Ada Alice; Tandoh, Theophilus; Nigam, Lokesh; Singer, Mahmoud; Caserta, Enrico; Murtadha, Mariam; Zhu, Yinghui; Moloudizargari, Milad; Sharma, Preeti; Napolitano, Ottavio; Winchester, Janet; Chowdhury, Arnab; Pozhitkov, Alex; Sanchez, James F; Vahed, Hawa; Marcucci, Guido; Coffey, Matt; Nuovo, Gerard; Sborov, Douglas W; Pichiorri, Flavia; Hofmeister, Craig C
多发性骨髓瘤
微生物学
骨髓瘤
细胞生物学
毒理研究
发表日期：2025
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Combination of pembrolizumab and pelareorep promotes anti-tumour immunity in advanced pancreatic adenocarcinoma (PDAC)

帕博利珠单抗和佩拉瑞普联合用药可促进晚期胰腺腺癌（PDAC）的抗肿瘤免疫反应

期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-023-02344-5
Mahalingam, Devalingam; Chen, Siqi; Xie, Ping; Loghmani, Houra; Heineman, Thomas; Kalyan, Aparna; Kircher, Sheetal; Helenowski, Irene B; Mi, Xinlei; Maurer, Victoria; Coffey, Matt; Mulcahy, Mary; Benson, Al-; Zhang, Bin
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2023
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Oncolytic virus treatment differentially affects the CD56(dim) and CD56(bright) NK cell subsets in vivo and regulates a spectrum of human NK cell activity

溶瘤病毒治疗对体内CD56(dim)和CD56(bright) NK细胞亚群的影响不同，并调节人类NK细胞的多种活性。

期刊:Immunology
影响因子:5
doi:10.1111/imm.13453
Wantoch, Michelle; Wilson, Erica B; Droop, Alastair P; Phillips, Sarah L; Coffey, Matt; El-Sherbiny, Yasser M; Holmes, Tim D; Melcher, Alan A; Wetherill, Laura F; Cook, Graham P
微生物学
CD5
CD56
细胞生物学
发表日期：2022
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Phase I trial of sargramostim/pelareorep therapy in pediatric patients with recurrent or refractory high-grade brain tumors

沙格司亭/佩拉瑞普疗法治疗复发性或难治性高级别脑肿瘤患儿的I期试验

期刊:NeuroOncology Advances
影响因子:4.1
doi:10.1093/noajnl/vdac085
Schuelke, Matthew R; Gundelach, Justin H; Coffey, Matt; West, Emma; Scott, Karen; Johnson, Derek R; Samson, Adel; Melcher, Alan; Vile, Richard G; Bram, Richard J
肿瘤
肿瘤免疫
神经科学
发表日期：2022
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Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

呼肠孤病毒诱导的细胞介导免疫可用于治疗耐药骨髓微环境中的多发性骨髓瘤

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2020-001803
Müller, Louise M E; Migneco, Gemma; Scott, Gina B; Down, Jenny; King, Sancha; Askar, Basem; Jennings, Victoria; Oyajobi, Babatunde; Scott, Karen; West, Emma; Ralph, Christy; Samson, Adel; Ilett, Elizabeth J; Muthana, Munitta; Coffey, Matt; Melcher, Alan; Parrish, Christopher; Cook, Gordon; Lawson, Michelle; Errington-Mais, Fiona
多发性骨髓瘤
治疗耐药
微生物学
骨髓瘤
细胞生物学
免疫/内分泌
发表日期：2021
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Oncolytic Reovirus-Mediated Recruitment of Early Innate Immune Responses Reverses Immunotherapy Resistance in Prostate Tumors

溶瘤呼肠孤病毒介导的早期先天免疫反应募集逆转前列腺肿瘤的免疫治疗耐药性

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2020.09.010
Annels, Nicola E; Simpson, Guy R; Denyer, Mick; Arif, Mehreen; Coffey, Matt; Melcher, Alan; Harrington, Kevin; Vile, Richard; Pandha, Hardev
肿瘤
肿瘤免疫
治疗耐药
微生物学
免疫/内分泌
发表日期：2021
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Pembrolizumab in Combination with the Oncolytic Virus Pelareorep and Chemotherapy in Patients with Advanced Pancreatic Adenocarcinoma: A Phase Ib Study

帕博利珠单抗联合溶瘤病毒Pelareorep和化疗治疗晚期胰腺腺癌患者：一项Ib期研究

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-19-2078
Mahalingam, Devalingam; Wilkinson, Grey A; Eng, Kevin H; Fields, Paul; Raber, Patrick; Moseley, Jennifer L; Cheetham, Karol; Coffey, Matt; Nuovo, Gerard; Kalinski, Pawel; Zhang, Bin; Arora, Sukeshi Patel; Fountzilas, Christos
微生物学
肿瘤
肿瘤免疫
发表日期：2020
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Immune characterization of metastatic colorectal cancer patients post reovirus administration.

转移性结直肠癌患者接受呼肠孤病毒治疗后的免疫特征分析

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/s12885-020-07038-2
Parakrama Ruwan, Fogel Elisha, Chandy Carol, Augustine Titto, Coffey Matt, Tesfa Lydia, Goel Sanjay, Maitra Radhashree
肿瘤
肠癌
肿瘤免疫
发表日期：2020
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Combination Therapy with Reovirus and ATM Inhibitor Enhances Cell Death and Virus Replication in Canine Melanoma

呼肠孤病毒与ATM抑制剂联合疗法可增强犬黑色素瘤细胞死亡和病毒复制

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2019.08.003
Igase, Masaya; Shibutani, Shusaku; Kurogouchi, Yosuke; Fujiki, Noriyuki; Hwang, Chung Chew; Coffey, Matt; Noguchi, Shunsuke; Nemoto, Yuki; Mizuno, Takuya
黑色素瘤
微生物学
ATM
细胞生物学
Canine
发表日期：2019
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