SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer prodrug that cross-links DNA and exerts highly potent antitumor activity
SG2285 是一种新型 C2-芳基取代的吡咯并苯并二氮杂卓二聚体前药，可交联 DNA 并发挥高效的抗肿瘤活性。
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-10-0790
Hartley, John A; Hamaguchi, Anzu; Coffils, Marissa; Martin, Christopher R H; Suggitt, Marie; Chen, Zhizhi; Gregson, Stephen J; Masterson, Luke A; Tiberghien, Arnaud C; Hartley, Janet M; Pepper, Christopher; Lin, Thet Thet; Fegan, Christopher; Thurston, David E; Howard, Philip W
