日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping single-cell diploid chromatin fiber architectures using DAF-seq

利用DAF-seq技术绘制单细胞二倍体染色质纤维结构图谱

Swanson, Elliott G; Mao, Yizi; Mallory, Benjamin J; Vollger, Mitchell R; Bohaczuk, Stephanie C; Oliveira, Christopher B; Lyon, Daniel B; Ranchalis, Jane; Parmalee, Nancy L; Cohen, Barak A; Bennett, James T; Stergachis, Andrew B

Identification of functional non-coding variants associated with orofacial cleft.

鉴定与唇腭裂相关的非编码功能变异

Kumari Priyanka, Friedman Ryan Z, Curtis Sarah W, Pi Lira, Paraiso Kitt, Visel Axel, Rhea Lindsey, Dunnwald Martine, Patni Anjali P, Mar Daniel, Bomsztyk Karol, Mathieu Julie, Ruohola-Baker Hannele, Leslie-Clarkson Elizabeth J, White Michael A, Cohen Barak A, Cornell Robert A

Systematic evaluation of metatranscriptomic differential gene expression in silico, in vitro, and in vivo enables elucidation of inter-species cross-feeding

通过计算机模拟、体外和体内实验对宏转录组差异基因表达进行系统评估,可以阐明物种间的交叉喂养机制。

Lee, Evan M; McNulty, Nathan P; Cheng, Jiye; Chang, Hao-Wei; Hibberd, Matthew C; Cohen, Barak A; Gordon, Jeffrey I

Active learning of enhancers and silencers in the developing neural retina

发育中的神经视网膜中增强子和抑制子的主动学习

Friedman, Ryan Z; Ramu, Avinash; Lichtarge, Sara; Wu, Yawei; Tripp, Lloyd; Lyon, Daniel; Myers, Connie A; Granas, David M; Gause, Maria; Corbo, Joseph C; Cohen, Barak A; White, Michael A

Massively parallel characterization of insulator activity across the genome

对全基因组绝缘子活性进行大规模并行表征

Hong, Clarice K Y; Wu, Yawei; Erickson, Alyssa A; Li, Jie; Federico, Arnold J; Cohen, Barak A

Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

CRX中的致病变异对光感受器中的增强子和沉默子具有不同的顺式调控作用。

Shepherdson, James L; Friedman, Ryan Z; Zheng, Yiqiao; Sun, Chi; Oh, Inez Y; Granas, David M; Cohen, Barak A; Chen, Shiming; White, Michael A

Transcription factor interactions explain the context-dependent activity of CRX binding sites

转录因子相互作用解释了CRX结合位点的上下文依赖性活性

Loell, Kaiser J; Friedman, Ryan Z; Myers, Connie A; Corbo, Joseph C; Cohen, Barak A; White, Michael A

The origins and functional effects of postzygotic mutations throughout the human life span

人类一生中合子后突变的起源和功能影响

Rockweiler, Nicole B; Ramu, Avinash; Nagirnaja, Liina; Wong, Wing H; Noordam, Michiel J; Drubin, Casey W; Huang, Ni; Miller, Brian; Todres, Ellen Z; Vigh-Conrad, Katinka A; Zito, Antonino; Small, Kerrin S; Ardlie, Kristin G; Cohen, Barak A; Conrad, Donald F

A single-cell massively parallel reporter assay detects cell-type-specific gene regulation.

单细胞大规模并行报告基因检测可检测细胞类型特异性基因调控

Zhao Siqi, Hong Clarice K Y, Myers Connie A, Granas David M, White Michael A, Corbo Joseph C, Cohen Barak A

Active learning of enhancer and silencer regulatory grammar in photoreceptors

光感受器中增强子和沉默子调控语法的主动学习

Friedman, Ryan Z; Ramu, Avinash; Lichtarge, Sara; Myers, Connie A; Granas, David M; Gause, Maria; Corbo, Joseph C; Cohen, Barak A; White, Michael A