日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Covalent inhibition of pro-apoptotic BAX.

共价抑制促凋亡蛋白BAX

McHenry Matthew W, Shi Peiwen, Camara Christina M, Cohen Daniel T, Rettenmaier T Justin, Adhikary Utsarga, Gygi Micah A, Yang Ka, Gygi Steven P, Wales Thomas E, Engen John R, Wells James A, Walensky Loren D

Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.

通过二硫键连接鉴定抗凋亡蛋白BFL-1的共价分子抑制剂

Harvey Edward P, Hauseman Zachary J, Cohen Daniel T, Rettenmaier T Justin, Lee Susan, Huhn Annissa J, Wales Thomas E, Seo Hyuk-Soo, Luccarelli James, Newman Catherine E, Guerra Rachel M, Bird Gregory H, Dhe-Paganon Sirano, Engen John R, Wells James A, Walensky Loren D

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

一种利用多肽和蛋白质对复杂小分子进行后期功能化的化学选择性策略

Cohen, Daniel T; Zhang, Chi; Fadzen, Colin M; Mijalis, Alexander J; Hie, Liana; Johnson, Kenneth D; Shriver, Zachary; Plante, Obadiah; Miller, Scott J; Buchwald, Stephen L; Pentelute, Bradley L

Amide-forming chemical ligation via O-acyl hydroxamic acids

通过 O-酰基羟肟酸进行酰胺形成化学连接

Dunkelmann, Daniel L; Hirata, Yuki; Totaro, Kyle A; Cohen, Daniel T; Zhang, Chi; Gates, Zachary P; Pentelute, Bradley L

Cdc42 regulates the cellular localization of Cdc42ep1 in controlling neural crest cell migration

Cdc42 调节 Cdc42ep1 的细胞定位以控制神经嵴细胞迁移

Shlomi Cohen, Daniel T Kovari, Wenbin Wei, Rebecca Keate, Jennifer E Curtis, Shuyi Nie

A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products

卡宾催化策略在原伊鲁丹天然产物合成中的应用

Hovey, M Todd; Cohen, Daniel T; Walden, Daniel M; Cheong, Paul H-Y; Scheidt, Karl A

An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

一种用于未保护肽中硒代半胱氨酸化学选择性芳基化的极性反转方法

Cohen, Daniel T; Zhang, Chi; Pentelute, Bradley L; Buchwald, Stephen L

Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media

在水相介质中,钯催化的(杂)芳基卤化物和三氟甲磺酸酯的温和氰化反应

Cohen, Daniel T; Buchwald, Stephen L

Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

通过串联 NHC 催化动态动力学拆分和室温脱羧反应合成功能化环戊烯:机理解析及合成应用

Cohen, Daniel T; Johnston, Ryne C; Rosson, Nicholas T; Cheong, Paul Ha-Yeon; Scheidt, Karl A

Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis

动态外消旋体的催化动力学拆分:N-杂环卡宾催化高立体选择性β-内酯的形成

Johnston, Ryne C; Cohen, Daniel T; Eichman, Chad C; Scheidt, Karl A; Cheong, Paul Ha-Yeon