日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy

间日疟原虫疟疾候选疫苗VMP001/AS01B在未感染过疟疾的成年人中的1/2a期试验:安全性、免疫原性和有效性

Bennett, Jason W; Yadava, Anjali; Tosh, Donna; Sattabongkot, Jetsumon; Komisar, Jack; Ware, Lisa A; McCarthy, William F; Cowden, Jessica J; Regules, Jason; Spring, Michele D; Paolino, Kristopher; Hartzell, Joshua D; Cummings, James F; Richie, Thomas L; Lumsden, Joanne; Kamau, Edwin; Murphy, Jittawadee; Lee, Cynthia; Parekh, Falgunee; Birkett, Ashley; Cohen, Joe; Ballou, W Ripley; Polhemus, Mark E; Vanloubbeeck, Yannick F; Vekemans, Johan; Ockenhouse, Christian F

OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory macrophages

OPN-a 通过增加促炎性巨噬细胞的募集和激活来诱发肌肉炎症

Gina M Many, Yasuyuki Yokosaki, Kitipong Uaesoontrachoon, Peter P Nghiem, Luca Bello, Sherry Dadgar, Ying Yin, Jesse M Damsker, Heather B Cohen, Joe N Kornegay, Marcas M Bamman, David M Mosser, Kanneboyina Nagaraju, Eric P Hoffman0

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults

Ad35.CS.01-RTS,S/AS01 异源初免加强疫苗对健康未感染疟疾成年人疟原虫攻击的效力

Ockenhouse, Christian F; Regules, Jason; Tosh, Donna; Cowden, Jessica; Kathcart, April; Cummings, James; Paolino, Kristopher; Moon, James; Komisar, Jack; Kamau, Edwin; Oliver, Thomas; Chhoeu, Austin; Murphy, Jitta; Lyke, Kirsten; Laurens, Matthew; Birkett, Ashley; Lee, Cynthia; Weltzin, Rich; Wille-Reece, Ulrike; Sedegah, Martha; Hendriks, Jenny; Versteege, Isabella; Pau, Maria Grazia; Sadoff, Jerold; Vanloubbeeck, Yannick; Lievens, Marc; Heerwegh, Dirk; Moris, Philippe; Guerra Mendoza, Yolanda; Jongert, Erik; Cohen, Joe; Voss, Gerald; Ballou, W Ripley; Vekemans, Johan

Heterologous prime-boost regimens with a recombinant chimpanzee adenoviral vector and adjuvanted F4 protein elicit polyfunctional HIV-1-specific T-Cell responses in macaques

采用重组黑猩猩腺病毒载体和佐剂F4蛋白的异源初免-加强免疫方案,可在猕猴体内诱导多功能HIV-1特异性T细胞反应。

Lorin, Clarisse; Vanloubbeeck, Yannick; Baudart, Sébastien; Ska, Michaël; Bayat, Babak; Brauers, Geoffroy; Clarinval, Géraldine; Donner, Marie-Noëlle; Marchand, Martine; Koutsoukos, Marguerite; Mettens, Pascal; Cohen, Joe; Voss, Gerald

Adenovirus E1A recruits the human Paf1 complex to enhance transcriptional elongation

腺病毒 E1A 募集人类 Paf1 复合物来增强转录延长

Gregory J Fonseca, Michael J Cohen, Joe S Mymryk

Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines: randomized, double-blind study in malaria-naïve adults

评估RTS,S/AS01和RTS,S/AS02佐剂疫苗的免疫反应:一项针对未感染过疟疾的成年人的随机、双盲研究

Leroux-Roels, Geert; Leroux-Roels, Isabel; Clement, Frédéric; Ofori-Anyinam, Opokua; Lievens, Marc; Jongert, Erik; Moris, Philippe; Ballou, W Ripley; Cohen, Joe

Induction and regulation of T-cell immunity by the novel tuberculosis vaccine M72/AS01 in South African adults

新型结核病疫苗M72/AS01在南非成年人中诱导和调节T细胞免疫

Day, Cheryl L; Tameris, Michele; Mansoor, Nazma; van Rooyen, Michele; de Kock, Marwou; Geldenhuys, Hennie; Erasmus, Mzwandile; Makhethe, Lebohang; Hughes, E Jane; Gelderbloem, Sebastian; Bollaerts, Anne; Bourguignon, Patricia; Cohen, Joe; Demoitié, Marie-Ange; Mettens, Pascal; Moris, Philippe; Sadoff, Jerald C; Hawkridge, Anthony; Hussey, Gregory D; Mahomed, Hassan; Ofori-Anyinam, Opokua; Hanekom, Willem A

Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications

疟疾血液期疫苗等位基因特异性效力的分子基础:对疫苗研发的启示

Ouattara, Amed; Takala-Harrison, Shannon; Thera, Mahamadou A; Coulibaly, Drissa; Niangaly, Amadou; Saye, Renion; Tolo, Youssouf; Dutta, Sheetij; Heppner, D Gray; Soisson, Lorraine; Diggs, Carter L; Vekemans, Johan; Cohen, Joe; Blackwelder, William C; Dube, Tina; Laurens, Matthew B; Doumbo, Ogobara K; Plowe, Christopher V

Does a kinematically aligned total knee arthroplasty restore function without failure regardless of alignment category?

运动学对齐的全膝关节置换术能否在不考虑对齐类别的情况下恢复功能而不失败?

Howell, Stephen M; Howell, Stacey J; Kuznik, Kyle T; Cohen, Joe; Hull, Maury L

Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01

两项 1 期串联研究的结果评估了疫苗候选抗原恶性疟原虫 FVO 裂殖子表面蛋白-1 (MSP1(42)) 与佐剂系统 AS01 联合肌内注射的安全性、反应原性和免疫原性。

Otsyula, Nekoye; Angov, Evelina; Bergmann-Leitner, Elke; Koech, Margaret; Khan, Farhat; Bennett, Jason; Otieno, Lucas; Cummings, James; Andagalu, Ben; Tosh, Donna; Waitumbi, John; Richie, Nancy; Shi, Meng; Miller, Lori; Otieno, Walter; Otieno, Godfrey Allan; Ware, Lisa; House, Brent; Godeaux, Olivier; Dubois, Marie-Claude; Ogutu, Bernhards; Ballou, W Ripley; Soisson, Lorraine; Diggs, Carter; Cohen, Joe; Polhemus, Mark; Heppner, D Gray Jr; Ockenhouse, Christian F; Spring, Michele D