日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fragment-Based Development of NSP14 Exonuclease Inhibitors Confounded by Batch-to-Batch Variability

基于片段的NSP14核酸外切酶抑制剂开发受批次间差异的影响

Coker, Jesse A; Sun, Rong; Polzer, Paul M; Romigh, Todd; Goins, Christopher M; Wang, Nancy S; Jung, Jae U; Stauffer, Shaun R

METTL16 promotes taxane resistance in Triple-Negative Breast Cancer through m (6) A-dependent translational upregulation of ABCB1

METTL16 通过 m(6)A 依赖的 ABCB1 翻译上调促进三阴性乳腺癌对紫杉烷类药物的耐药性。

Holvey-Bates, Elise G; Coker, Jesse A; Lindner, Daniel J; Agarwal, Anchal; Bhushan, Anand; Parker, Yvonne; Gilmore, Hannah; Komar, Anton A; Stark, George R; De, Sarmishtha

MCL1 may not mediate chemoresistance.

MCL1 可能不会介导化疗耐药性

Emhoff Kylin A, Chung Kunho, Zhang Dongmei, Willard Belinda, Chan Timothy, Jha Babal Kant, Stauffer Shaun R, Coker Jesse A, Melenhorst Jan Joseph

Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer.

肾癌中 SLC1A1/EAAT3 选择性抑制剂的机制和结构导向优化

Koochaki Pooneh, Qiu Biao, Coker Jesse A, Earsley Alexander, Wang Nancy S, Romigh Todd, Goins Christopher M, Stauffer Shaun R, Boudker Olga, Chakraborty Abhishek A

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

苯并咪唑衍生物激活剂对 RAS 上 SOS1 介导的核苷酸交换的发现和基于结构的优化

Hodges, Timothy R; Abbott, Jason R; Little, Andrew J; Sarkar, Dhruba; Salovich, James M; Howes, Jennifer E; Akan, Denis T; Sai, Jiqing; Arnold, Allison L; Browning, Carrie; Burns, Michael C; Sobolik, Tammy; Sun, Qi; Beesetty, Yugandhar; Coker, Jesse A; Scharn, Dirk; Stadtmueller, Heinz; Rossanese, Olivia W; Phan, Jason; Waterson, Alex G; McConnell, Darryl B; Fesik, Stephen W