日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Current use of pre-clinical models for evaluation of human adenovirus-based cancer therapeutics

目前利用临床前模型评估基于人腺病毒的癌症疗法

Cole, David K; Khanolkar, Rahul C; Davies, James A; Gerry, Andrew B

A CD1c lipid agnostic T cell receptor bispecific engager redirects T cells against CD1c(+) cells.

CD1c 脂质非依赖性 T 细胞受体双特异性衔接器可将 T 细胞重新定向攻击 CD1c(+) 细胞

Szoke-Kovacs Rita, Khakoo Sophie, Rangel Victor Lopes, Della Cristina Pietro, Pentier Johanne, Khanolkar Rahul, El-Ajouz Sam, Simmons Robert, Cole David K, Gogolak Peter, Salio Mariolina, Karuppiah Vijaykumar

Characterization of Human CD8αβ Interaction With Classical and Unconventional MHC Molecules

人类CD8αβ与经典和非经典MHC分子相互作用的特征分析

de Wet, Ben; Simmons, Robert Alan; Suckling, Richard J; Szoke-Kovacs, Rita; Mansour, Salah; Lepore, Marco; Cole, David K; Jaworski, Jakub; Chapman, Alexandra L; Aleksic, Milos

HLA A*24:02-restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes

型糖尿病中,HLA A*24:02 限制性 T 细胞受体可交叉识别细菌和胰岛素原肽。

Dolton, Garry; Bulek, Anna; Wall, Aaron; Thomas, Hannah; Hopkins, Jade R; Rius, Cristina; Galloway, Sarah Ae; Whalley, Thomas; Tan, Li Rong; Morin, Théo; Omidvar, Nader; Fuller, Anna; Topley, Katie; Hasan, Md Samiul; Jain, Shikha; D'Souza, Nirupa; Hodges-Hoyland, Thomas; Spiller, Owen B; Kronenberg-Versteeg, Deborah; Szomolay, Barbara; van den Berg, Hugo A; Jones, Lucy C; Peakman, Mark; Cole, David K; Rizkallah, Pierre J; Sewell, Andrew K

Unconventional modes of peptide-HLA-I presentation change the rules of TCR engagement

非常规的肽-HLA-I呈递方式改变了TCR结合的规则

Hopkins, Jade R; MacLachlan, Bruce J; Harper, Stephen; Sewell, Andrew K; Cole, David K

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

四级结构松弛引起的T细胞抗原受体信号传导的变构激活

Lanz, Anna-Lisa; Masi, Giulia; Porciello, Nicla; Cohnen, André; Cipria, Deborah; Prakaash, Dheeraj; Bálint, Štefan; Raggiaschi, Roberto; Galgano, Donatella; Cole, David K; Lepore, Marco; Dushek, Omer; Dustin, Michael L; Sansom, Mark S P; Kalli, Antreas C; Acuto, Oreste

The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism.

人类腺病毒 49 型的纤维旋钮蛋白利用一种新型细胞进入机制,介导对癌细胞系的高效和广泛感染

Baker Alexander T, Davies James A, Bates Emily A, Moses Elise, Mundy Rosie M, Marlow Gareth, Cole David K, Bliss Carly M, Rizkallah Pierre J, Parker Alan L

Engineering soluble T-cell receptors for therapy

工程改造可溶性T细胞受体用于治疗

Robinson, Ross A; McMurran, Catriona; McCully, Michelle L; Cole, David K

VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium

2019 年 VDJdb:数据库扩展、新的分析基础设施和 T 细胞受体基序汇编

Bagaev, Dmitry V; Vroomans, Renske M A; Samir, Jerome; Stervbo, Ulrik; Rius, Cristina; Dolton, Garry; Greenshields-Watson, Alexander; Attaf, Meriem; Egorov, Evgeny S; Zvyagin, Ivan V; Babel, Nina; Cole, David K; Godkin, Andrew J; Sewell, Andrew K; Kesmir, Can; Chudakov, Dmitriy M; Luciani, Fabio; Shugay, Mikhail

Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy

增强人类T细胞受体亲和力结合的分子机制及其在免疫治疗中的应用

Crean, Rory M; MacLachlan, Bruce J; Madura, Florian; Whalley, Thomas; Rizkallah, Pierre J; Holland, Christopher J; McMurran, Catriona; Harper, Stephen; Godkin, Andrew; Sewell, Andrew K; Pudney, Christopher R; van der Kamp, Marc W; Cole, David K