日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results

靶向淋巴结的mKRAS特异性两亲性疫苗治疗胰腺癌和结直肠癌:AMPLIFY-201 I期试验最终结果

Zev A Wainberg ,Colin D Weekes ,Muhammad Furqan ,Pashtoon M Kasi ,Craig E Devoe ,Alexis D Leal ,Vincent Chung ,James R Perry ,Thian Kheoh ,Lisa K McNeil ,Esther Welkowsky ,Peter C DeMuth ,Christopher M Haqq ,Shubham Pant # ,Eileen M O'Reilly #

Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

淋巴结靶向、mKRAS特异性两亲性疫苗在胰腺癌和结直肠癌中的应用:AMPLIFY-201 I期试验

Shubham Pant ,Zev A Wainberg ,Colin D Weekes ,Muhammad Furqan ,Pashtoon M Kasi ,Craig E Devoe ,Alexis D Leal ,Vincent Chung ,Olca Basturk ,Haley VanWyk ,Amy M Tavares ,Lochana M Seenappa ,James R Perry ,Thian Kheoh ,Lisa K McNeil ,Esther Welkowsky ,Peter C DeMuth ,Christopher M Haqq ,Eileen M O'Reilly

Pharmacokinetic and pharmacodynamic analysis of circulating biomarkers of anti-NRP1, a novel antiangiogenesis agent, in two phase I trials in patients with advanced solid tumors

新型抗血管生成药物抗 NRP1 在晚期实体肿瘤患者两项 I 期试验中的循环生物标志物的药代动力学和药效学分析

Yan Xin, Jessica Li, Jenny Wu, Rashell Kinard, Colin D Weekes, Amita Patnaik, Patricia Lorusso, Rainer Brachmann, Raymond K Tong, Yibing Yan, Ryan Watts, Shuang Bai, Priti S Hegde

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

胰腺癌的单细胞核和空间转录组分析揭示了与新辅助治疗相关的多细胞动态变化

William L Hwang # ,Karthik A Jagadeesh # ,Jimmy A Guo # ,Hannah I Hoffman # ,Payman Yadollahpour ,Jason W Reeves ,Rahul Mohan ,Eugene Drokhlyansky ,Nicholas Van Wittenberghe ,Orr Ashenberg ,Samouil L Farhi ,Denis Schapiro ,Prajan Divakar ,Eric Miller ,Daniel R Zollinger ,George Eng ,Jason M Schenkel ,Jennifer Su ,Carina Shiau ,Patrick Yu ,William A Freed-Pastor ,Domenic Abbondanza ,Arnav Mehta ,Joshua Gould ,Conner Lambden ,Caroline B M Porter ,Alexander Tsankov ,Danielle Dionne ,Julia Waldman ,Michael S Cuoco ,Lan Nguyen ,Toni Delorey ,Devan Phillips ,Jaimie L Barth ,Marina Kem ,Clifton Rodrigues ,Debora Ciprani ,Jorge Roldan ,Piotr Zelga ,Vjola Jorgji ,Jonathan H Chen ,Zackery Ely ,Daniel Zhao ,Kit Fuhrman ,Robin Fropf ,Joseph M Beechem ,Jay S Loeffler ,David P Ryan ,Colin D Weekes ,Cristina R Ferrone ,Motaz Qadan ,Martin J Aryee ,Rakesh K Jain ,Donna S Neuberg ,Jennifer Y Wo ,Theodore S Hong ,Ramnik Xavier ,Andrew J Aguirre ,Orit Rozenblatt-Rosen ,Mari Mino-Kenudson ,Carlos Fernandez-Del Castillo ,Andrew S Liss ,David T Ting ,Tyler Jacks ,Aviv Regev

Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial

在 II 期试验中,放射疗法增强了微卫星稳定型结直肠癌和胰腺腺癌的免疫疗法反应。

Aparna R Parikh #,Annamaria Szabolcs #,Jill N Allen,Jeffrey W Clark,Jennifer Y Wo,Michael Raabe,Hannah Thel,David Hoyos,Arnav Mehta,Sanya Arshad,David J Lieb,Lorraine C Drapek,Lawrence S Blaszkowsky,Bruce J Giantonio,Colin D Weekes,Andrew X Zhu,Lipika Goyal,Ryan D Nipp,Jon S Dubois,Emily E Van Seventer,Bronwen E Foreman,Lauren E Matlack,Leilana Ly,Jessica A Meurer,Nir Hacohen,David P Ryan,Beow Y Yeap,Ryan B Corcoran,Benjamin D Greenbaum,David T Ting,Theodore S Hong

Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial

FOLFIRINOX 联合氯沙坦全新辅助治疗,随后进行放化疗治疗局部晚期胰腺癌:一项 2 期临床试验

Janet E Murphy, Jennifer Y Wo, David P Ryan, Jeffrey W Clark, Wenqing Jiang, Beow Y Yeap, Lorraine C Drapek, Leilana Ly, Christian V Baglini, Lawrence S Blaszkowsky, Cristina R Ferrone, Aparna R Parikh, Colin D Weekes, Ryan D Nipp, Eunice L Kwak, Jill N Allen, Ryan B Corcoran, David T Ting, Jason E

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

CD147:一种小分子转运辅助蛋白,位于癌症和代谢重编程的多个特征的交叉点

Agnieszka A Kendrick, Johnathon Schafer, Monika Dzieciatkowska, Travis Nemkov, Angelo D'Alessandro, Deepika Neelakantan, Heide L Ford, Chad G Pearson, Colin D Weekes, Kirk C Hansen, Elan Z Eisenmesser