日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The PRMT5-splicing axis is a critical oncogenic vulnerability that regulates detained intron splicing

PRMT5 剪接轴是调节阻滞内含子剪接的关键致癌弱点

Colin E Fowler, Natalie A O'Hearn, Griffin J Salus, Arundeep Singh, Paul L Boutz, Jacqueline A Lees

Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel

对 PRMT5 抑制的获得性耐药性会同时诱发对紫杉醇的侧支敏感性

Helen S Mueller, Colin E Fowler, Simona Dalin, Enrico Moiso, Tee Udomlumleart, Salil Garg, Michael T Hemann, Jacqueline A Lees

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

SERM/SERD 巴曲昔芬破坏 ESR1 螺旋 12,以克服乳腺癌细胞获得性激素耐药性

Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Ross Han, Muriel Lainé, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad