日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

PBT2 靶向 Abeta 作为阿尔茨海默病改良疗法的安全性、有效性和生物标志物发现:一项 IIa 期、双盲、随机、安慰剂对照试验

Lars Lannfelt, Kaj Blennow, Henrik Zetterberg, Stellan Batsman, David Ames, John Harrison, Colin L Masters, Steve Targum, Ashley I Bush, Ross Murdoch, Janet Wilson, Craig W Ritchie; PBT2-201-EURO study group

Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils

单分子指纹识别揭示了不同 α-突触核蛋白原纤维多态性的种子扩增试验中的不同生长机制

Derrick Lau, Yuan Tang, Vijaya Kenche, Thomas Copie, Daryan Kempe, Eve Jary, Noah J Graves, Maté Biro, Colin L Masters, Nicolas Dzamko, Yann Gambin, Emma Sierecki

Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer's Disease Across Distinct Brain Regions

揭示阿尔茨海默病中不同脑区 ApoE 基因型驱动的蛋白质组学和脂质组学改变

Melanie T Odenkirk, Xueyun Zheng, Jennifer E Kyle, Kelly G Stratton, Carrie D Nicora, Kent J Bloodsworth, Catriona A Mclean, Colin L Masters, Matthew E Monroe, James D Doecke, Richard D Smith, Kristin E Burnum-Johnson, Blaine R Roberts, Erin S Baker

Biomarker clustering in autosomal dominant Alzheimer's disease

常染色体显性阿尔茨海默病的生物标志物聚集

Patrick H Luckett, Charlie Chen, Brian A Gordon, Julie Wisch, Sarah B Berman, Jasmeer P Chhatwal, Carlos Cruchaga, Anne M Fagan, Martin R Farlow, Nick C Fox, Mathias Jucker, Johannes Levin, Colin L Masters, Hiroshi Mori, James M Noble, Stephen Salloway, Peter R Schofield, Adam M Brickman, William S

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease

IL1RL1基因变异会降低可溶性ST2水平,并降低女性阿尔茨海默病患者中APOE-ε4的风险效应。

Yuanbing Jiang,Xiaopu Zhou,Hiu Yi Wong,Li Ouyang,Fanny C F Ip,Vicky M N Chau,Shun-Fat Lau,Wei Wu,Daniel Y K Wong,Heukjin Seo,Wing-Yu Fu,Nicole C H Lai,Yuewen Chen,Yu Chen,Estella P S Tong,Maryam Shoai,Benoit Lehallier,Patricia Morán Losada,Eleanor O'Brien,Tenielle Porter,Simon M Laws,John Hardy,Tony Wyss-Coray,Colin L Masters,Amy K Y Fu,Nancy Y Ip

Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques

血浆淀粉样蛋白-β 42/40 检测阿尔茨海默病淀粉样斑块的验证

Yan Li, Suzanne E Schindler, James G Bollinger, Vitaliy Ovod, Kwasi G Mawuenyega, Michael W Weiner, Leslie M Shaw, Colin L Masters, Christopher J Fowler, John Q Trojanowski, Magdalena Korecka, Ralph N Martins, Shorena Janelidze, Oskar Hansson, Randall J Bateman

Identification of Leukocyte Surface P2X7 as a Biomarker Associated with Alzheimer's Disease

鉴定白细胞表面 P2X7 为与阿尔茨海默病相关的生物标志物

Yihan Li, Xin Huang, Christopher Fowler, Yen Y Lim, Simon M Laws, Noel Faux, James D Doecke, Brett Trounson, Kelly Pertile, Rebecca Rumble, Vincent Doré, Victor L Villemagne, Christopher C Rowe, James S Wiley, Paul Maruff, Colin L Masters, Ben J Gu0

Characterization of brain-derived extracellular vesicle lipids in Alzheimer's disease

阿尔茨海默病中脑源性细胞外囊泡脂质的表征

Huaqi Su, Yepy H Rustam, Colin L Masters, Enes Makalic, Catriona A McLean, Andrew F Hill, Kevin J Barnham, Gavin E Reid, Laura J Vella

A six-metabolite panel as potential blood-based biomarkers for Parkinson's disease

六种代谢物组可作为帕金森病的潜在血液生物标志物

Stephan Klatt, James D Doecke, Anne Roberts, Berin A Boughton, Colin L Masters, Malcolm Horne, Blaine R Roberts

Deficits in Monocyte Function in Age Related Macular Degeneration: A Novel Systemic Change Associated With the Disease

年龄相关性黄斑变性中的单核细胞功能缺陷:与该疾病相关的一种新的系统性变化

Ben J Gu, Xin Huang, Pavan K Avula, Emily Caruso, Candace Drysdale, Kirstan A Vessey, Amber Ou, Christopher Fowler, Tian-Hua Liu, Yong Lin, Adam Horton, Colin L Masters, James S Wiley, Robyn H Guymer, Erica L Fletcher