日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PET-MRI biomarkers reveal efficacy of a novel NLRP3 inhibitor in Parkinson's disease models

PET-MRI生物标志物揭示了一种新型NLRP3抑制剂在帕金森病模型中的疗效

Albornoz, Eduardo A; Mardon, Karine; Bhalla, Rajiv; Kumar, Vinod; Stimson, Damion H R; Cowin, Gary; Cui, Cedric S; Butler, Mark S; Pelingon, Ruby; Gordon, Richard; Coll, Rebecca C; Schroder, Kate; Halai, Reena; MacLeod, Angus M; Matthews, Kim; Robertson, Avril A B; Cooper, Matthew A; Woodruff, Trent M

Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma

在胶质母细胞瘤中,病毒趋化因子受体US28的转录活性是由质膜而非内体Gq信号传导驱动的。

Daly, Carole; Wright, Adam; Heukers, Raimond; McKee, Chloe M; Coll, Rebecca C; Evergren, Emma; Smit, Martine J; Thomsen, Alex R B; Plouffe, Bianca

Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS).

IL-18 介导的铁蛋白升高与急性呼吸窘迫综合征 (ARDS) 的全身炎症和死亡率相关

Mehta Puja, Samanta Romit J, Wick Katherine, Coll Rebecca C, Mawhinney Thea, McAleavey Patrick G, Boyle Andrew J, Conlon John, Shankar-Hari Manu, Rogers Angela, Calfee Carolyn S, Matthay Michael A, Summers Charlotte, Chambers Rachel Clare, McAuley Daniel Francis, O'Kane Cecilia M

Role reversal: adaptive immunity instructs inflammasome activation for anti-viral defence

角色互换:适应性免疫指导炎症小体激活以进行抗病毒防御

Coll, Rebecca C

Mitochondrial DNA synthesis fuels NLRP3 activation

线粒体DNA合成促进NLRP3激活。

Coll, Rebecca C; Holley, Caroline L; Schroder, Kate

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

NLRP3炎症小体在骨髓增生异常综合征表型中发挥驱动作用

Basiorka, Ashley A; McGraw, Kathy L; Eksioglu, Erika A; Chen, Xianghong; Johnson, Joseph; Zhang, Ling; Zhang, Qing; Irvine, Brittany A; Cluzeau, Thomas; Sallman, David A; Padron, Eric; Komrokji, Rami; Sokol, Lubomir; Coll, Rebecca C; Robertson, Avril A B; Cooper, Matthew A; Cleveland, John L; O'Neill, Luke A; Wei, Sheng; List, Alan F