Higher levels of host-cell DNA methylation markers ZNF582 and ASCL1 on anal smears are predictive for progression to anal cancer in patients with previous high-grade lesions
肛门涂片中宿主细胞DNA甲基化标志物ZNF582和ASCL1水平升高可预测既往有高级别病变的患者进展为肛门癌。
期刊:EBioMedicine
影响因子:
doi:10.1016/j.ebiom.2025.105936
Ferré, Valentine Marie; Dupont, Axelle; Draullette, Mélanie; Valette, Emy; Collin, Gilles; Bucau, Margot; Siproudhis, Laurent; Staumont, Ghislain; Roy, Carine; Hesselink, Albertus Theodorus; Bouchard, Dominique; Radenne, Sylvie; Spindler, Lucas; Naji, Anas; Bergeron, Christine; Couvelard, Anne; Descamps, Diane; Steenbergen, Renske D M; Charpentier, Charlotte; Abramowitz, Laurent
肿瘤
表观遗传
肿瘤免疫
DNA甲基化
ASCL1
ASC
细胞生物学