日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HIV-1 transcription dominates over host gene activity at the HIV-1 integration site

在 HIV-1 整合位点,HIV-1 转录活性远高于宿主基因活性。

Weissman, Samuel; Yeh, Yang-Hui J; Viazmenski, Miriam; Kim, Rachel; Collora, Jack A; Steinhauser, Savannah; Ho, Ya-Chi

Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation

高危人群发展为类风湿性关节炎的特征是全身炎症以及T细胞和B细胞功能失调。

He, Ziyuan; Glass, Marla C; Venkatesan, Pravina; Feser, Marie L; Lazaro, Leander; Okada, Lauren Y; Tran, Nhung T T; He, Yudong D; Zaim, Samir Rachid; Bennett, Christy E; Ravisankar, Padmapriyadarshini; Dornisch, Elisabeth M; Ferrannini, Alexandra C; Arishi, Najeeb A; Asamoah, Ashley G; Barzideh, Saman; Becker, Lynne A; Bemis, Elizabeth A; Buckner, Jane H; Collora, Christopher E; Criley, Megan A L; Demoruelle, M Kristen; Fleischer, Chelsie L; Garber, Jessica; Genge, Palak C; Gong, Qiuyu; Graybuck, Lucas T; Gustafson, Claire E; Hattel, Brian C; Hernandez, Veronica; Heubeck, Alexander T; Kawelo, Erin K; Krishnan, Upaasana; Kuan, Emma L; Kuhn, Kristine A; LaFrance, Christian M; Lee, Kevin J; Li, Ruoxin; Lord, Cara; Mettey, Regina R; Moss, Laura; Musgrove, Blessing; Nguyen, Katherine Hy; Ochoa, Andrea; Parthasarathy, Vaishnavi; Pebworth, Mark-Phillip; Pedrick, Chong; Peng, Tao; Phalen, Cole G; Reading, Julian; Roll, Charles R; Seifert, Jennifer A; Siedschlag, Marguerite D; Speake, Cate; Striebich, Christopher C; Stuckey, Tyanna J; Swanson, Elliott G; Takada, Hideto; Thai, Tylor; Thomson, Zachary J; Trieu, Nguyen; Tsaltskan, Vlad; Wang, Wei; Weiss, Morgan D A; Westermann, Amy; Zhang, Fan; Boyle, David L; Goldrath, Ananda W; Bumol, Thomas F; Li, Xiao-Jun; Holers, V Michael; Skene, Peter J; Savage, Adam K; Firestein, Gary S; Deane, Kevin D; Torgerson, Troy R; Gillespie, Mark A

Medications for opioid use disorder shape immune responses during chronic HIV infection

治疗阿片类药物使用障碍的药物会影响慢性 HIV 感染期间的免疫反应。

Jack A Collora ,Savannah F Steinhauser ,Timothy C Davenport ,Daniel C Lin ,Amare Eshetu ,Samana Zeidi ,Rachel Kim ,Cynthia Frank ,Yuval Kluger ,Sandra A Springer ,Ya-Chi Ho

Single-cell epigenetic, transcriptional, and protein profiling of latent and active HIV-1 reservoir revealed that IKZF3 promotes HIV-1 persistence

对潜伏性和活动性 HIV-1 病毒库的单细胞表观遗传学、转录组和蛋白质组分析表明,IKZF3 促进 HIV-1 的持续存在。

Yulong Wei ,Timothy C Davenport ,Jack A Collora ,Haocong Katherine Ma ,Delia Pinto-Santini ,Javier Lama ,Ricardo Alfaro ,Ann Duerr ,Ya-Chi Ho

Integration site-dependent HIV-1 promoter activity shapes host chromatin conformation

整合位点依赖性的HIV-1启动子活性塑造宿主染色质构象

Jack A Collora ,Ya-Chi Ho

Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones

单细胞多组学揭示HIV-1在扩增的细胞毒性T细胞克隆中的持续存在

Jack A Collora ,Runxia Liu ,Delia Pinto-Santini ,Neal Ravindra ,Carmela Ganoza ,Javier R Lama ,Ricardo Alfaro ,Jennifer Chiarella ,Serena Spudich ,Karam Mounzer ,Pablo Tebas ,Luis J Montaner ,David van Dijk ,Ann Duerr ,Ya-Chi Ho

Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant

在类风湿性关节炎队列中前瞻性地识别亚临床间质性肺病与MUC5B启动子变异相关

Matson, Scott M; Deane, Kevin D; Peljto, Anna L; Bang, Tami J; Sachs, Peter B; Walts, Avram D; Collora, Christopher; Ye, Shuyu; Demoruelle, M Kristen; Humphries, Stephen M; Schwartz, David A; Lee, Joyce S

Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen

通过 CRISPR 抑制筛选发现,染色质和转录调节剂 SLTM 的抑制可增加 HIV-1 再激活

Savannah F Pedersen #, Jack A Collora #, Rachel N Kim #, Kerui Yang, Anya Razmi, Allison A Catalano, Yang-Hui Jimmy Yeh, Karam Mounzer, Pablo Tebas, Luis J Montaner, Ya-Chi Ho

The single-cell landscape of immunological responses of CD4+ T cells in HIV versus severe acute respiratory syndrome coronavirus 2

HIV 和严重急性呼吸综合征冠状病毒 2 中 CD4+ T 细胞免疫反应的单细胞图谱

Collora, Jack A; Liu, Runxia; Albrecht, Kristen; Ho, Ya-Chi

Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target

单细胞转录组图谱揭示了HIV-1驱动的宿主基因异常转录,并将其作为潜在的治疗靶点。

Liu, Runxia; Yeh, Yang-Hui Jimmy; Varabyou, Ales; Collora, Jack A; Sherrill-Mix, Scott; Talbot, C Conover Jr; Mehta, Sameet; Albrecht, Kristen; Hao, Haiping; Zhang, Hao; Pollack, Ross A; Beg, Subul A; Calvi, Rachela M; Hu, Jianfei; Durand, Christine M; Ambinder, Richard F; Hoh, Rebecca; Deeks, Steven G; Chiarella, Jennifer; Spudich, Serena; Douek, Daniel C; Bushman, Frederic D; Pertea, Mihaela; Ho, Ya-Chi