日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Correction to "Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process"

更正“天然产物提高了药物研发过程中的临床试验成功率”

Domingo-Fernández, Daniel; Gadiya, Yojana; Preto, António José; Krettler, Christoph A; Mubeen, Sarah; Allen, August; Healey, David; Colluru, Viswa

Defining the limits of plant chemical space: challenges and estimations

界定植物化学空间的界限:挑战与估算

Hart, Chloe Engler; Gadiya, Yojana; Kind, Tobias; Krettler, Christoph A; Gaetz, Matthew; Misra, Biswapriya B; Healey, David; Allen, August; Colluru, Viswa; Domingo-Fernández, Daniel

Exploring the known chemical space of the plant kingdom: insights into taxonomic patterns, knowledge gaps, and bioactive regions

探索植物界已知的化学空间:深入了解分类模式、知识空白和生物活性区域

Domingo-Fernández, Daniel; Gadiya, Yojana; Mubeen, Sarah; Healey, David; Norman, Bryan H; Colluru, Viswa

Modern drug discovery using ethnobotany: A large-scale cross-cultural analysis of traditional medicine reveals common therapeutic uses

利用民族植物学进行现代药物发现:一项大规模的跨文化传统医学分析揭示了常见的治疗用途

Domingo-Fernández, Daniel; Gadiya, Yojana; Mubeen, Sarah; Bollerman, Thomas Joseph; Healy, Matthew D; Chanana, Shaurya; Sadovsky, Rotem Gura; Healey, David; Colluru, Viswa

Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery

利用药物扰动和疾病特异性转录组特征,基于知识图谱的因果推理进行药物发现

Domingo-Fernández, Daniel; Gadiya, Yojana; Patel, Abhishek; Mubeen, Sarah; Rivas-Barragan, Daniel; Diana, Chris W; Misra, Biswapriya B; Healey, David; Rokicki, Joe; Colluru, Viswa

TLR Stimulation during T-cell Activation Lowers PD-1 Expression on CD8+ T Cells

细胞活化期间的 TLR 刺激会降低 CD8+ T 细胞上的 PD-1 表达

Christopher D Zahm, Viswa T Colluru, Sean J McIlwain, Irene M Ong, Douglas G McNeel

DNA vaccines for prostate cancer

前列腺癌的DNA疫苗

Zahm, Christopher D; Colluru, Viswa Teja; McNeel, Douglas G

Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8+ T Cells

高亲和力表位疫苗接种会增加 CD8+ T 细胞上的 PD-1 表达,从而削弱抗肿瘤功效

Christopher D Zahm, Viswa T Colluru, Douglas G McNeel

Preclinical and clinical development of DNA vaccines for prostate cancer

前列腺癌DNA疫苗的临床前和临床开发

Colluru, V T; Johnson, Laura E; Olson, Brian M; McNeel, Douglas G

B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines

淋巴细胞作为抗肿瘤 DNA 疫苗的直接抗原呈递细胞

Viswa Teja Colluru, Douglas G McNeel