日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer.

神经酰胺诱导的内质网应激是内分泌治疗耐药性乳腺癌的一个可靶向脆弱性

Pal Purab, Chitkara Shweta, Sarpey Godwin K, Alani Fatimah, Zhao Huiping, Ata Malik, Qu Jun, Schiff Rachel, Tonetti Debra, Greene Geoffrey L, Frasor Jonna, Atilla-Gokcumen Gunes Ekin, Coloff Jonathan L

Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis.

微环境中的精氨酸限制通过抑制脂质合成,使胰腺癌对多不饱和脂肪酸更加敏感

Jonker Patrick B, Sadullozoda Mumina, Cognet Guillaume, Saab Juan J Apiz, Sokol Kelly H, Wu Violet X, Kumari Deepa, Sheehan Colin, Ozgurses Mete E, Agovino Darby, Croley Grace, Patel Smit A, Bock-Hughes Althea, Macleod Kay F, Shah Hardik, Coloff Jonathan L, Lien Evan C, Muir Alexander

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

在人体生理介质中进行的药物筛选发现,尿酸是rigosertib疗效的抑制剂。

Rawat, Vipin; DeLear, Patrick; Prashanth, Prarthana; Ozgurses, Mete Emir; Tebeje, Anteneh; Burns, Philippa A; Conger, Kelly O; Solís, Christopher; Hasnain, Yasir; Novikova, Anna; Endress, Jennifer E; González-Sánchez, Paloma; Dong, Wentao; Stephanopoulos, Greg; DeNicola, Gina M; Harris, Isaac S; Sept, David; Mason, Frank M; Coloff, Jonathan L

The Diverse Functions of Non-Essential Amino Acids in Cancer

非必需氨基酸在癌症中的多种功能

Choi, Bo-Hyun; Coloff, Jonathan L

Corrigendum: Chaperone-mediated autophagy degrades mutant p53

更正:分子伴侣介导的自噬会降解突变型p53

Vakifahmetoglu-Norberg, Helin; Kim, Minsu; Xia, Hong-Guang; Iwanicki, Marcin P; Ofengeim, Dimitry; Coloff, Jonathan L; Pan, Lifeng; Ince, Tan A; Kroemer, Guido; Brugge, Joan S; Yuan, Junying

Combining amine metabolomics and quantitative proteomics of cancer cells using derivatization with isobaric tags

结合胺代谢组学和定量蛋白质组学,利用同位素标记衍生化技术研究癌细胞。

Murphy, J Patrick; Everley, Robert A; Coloff, Jonathan L; Gygi, Steven P

HIF1α and HIF2α exert distinct nutrient preferences in renal cells.

HIF1α 和 HIF2α 在肾细胞中表现出不同的营养偏好

Arreola Alexandra, Cowey C Lance, Coloff Jonathan L, Rathmell Jeffrey C, Rathmell W Kimryn

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation

Erk 通过 PDK4 调控丙酮酸脱氢酶的通量,从而调节细胞增殖。

Grassian, Alexandra R; Metallo, Christian M; Coloff, Jonathan L; Stephanopoulos, Gregory; Brugge, Joan S

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability

APC/CCdh1介导的Drp1稳定性调控线粒体形态

Horn, Sarah R; Thomenius, Michael J; Johnson, Erika Segear; Freel, Christopher D; Wu, Judy Q; Coloff, Jonathan L; Yang, Chih-Sheng; Tang, Wanli; An, Jie; Ilkayeva, Olga R; Rathmell, Jeffrey C; Newgard, Christopher B; Kornbluth, Sally

Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis

自噬提供营养,但可能导致Chop依赖性的Bim诱导,从而使缺乏生长因子的细胞对凋亡更加敏感。

Altman, Brian J; Wofford, Jessica A; Zhao, Yuxing; Coloff, Jonathan L; Ferguson, Emily C; Wieman, Heather L; Day, Amanda E; Ilkayeva, Olga; Rathmell, Jeffrey C