日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function

间歇性清除高表达p21的细胞可延长寿命,并对健康和身体机能带来持续益处。

Binsheng Wang ,Lichao Wang ,Nathan S Gasek ,Chia-Ling Kuo ,Jia Nie ,Taewan Kim ,Pengyi Yan ,Junyu Zhu ,Blake L Torrance ,Yueying Zhou ,Lisa C Flores ,Colton Allen ,Allison M Andrade ,Chun Guo ,Rachel L Cohn ,Evan R Jellison ,Jenna M Bartley ,George A Kuchel ,Sheng Li ,Tamar Pirtskhalava ,Tamar Tchkonia ,Sumit Yadav ,Laura Haynes ,James L Kirkland ,Yuji Ikeno ,Ming Xu

Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice

线粒体中硫氧还蛋白的过度表达对雄性 C57BL/6 小鼠的衰老和与年龄相关的疾病的影响最小

Madeline G Roman, Lisa C Flores, Geneva M Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Gene B Hubbard, Thomas L Saunders, Yuji Ikeno

Continuous overexpression of thioredoxin 1 enhances cancer development and does not extend maximum lifespan in male C57BL/6 mice

硫氧还蛋白 1 的持续过表达会促进癌症发展,并且不会延长雄性 C57BL/6 小鼠的最大寿命

Lisa C Flores, Madeline G Roman, Geneva M Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Gene B Hubbard, Thomas L Saunders, Yuji Ikeno