日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A polygenetic rat model of divergent aerobic capacity reveals a liver-brain interaction impacting Alzheimer's disease-like phenotypes

具有不同有氧能力的多基因大鼠模型揭示了肝脑相互作用对阿尔茨海默病样表型的影响

Lysaker, Colton R; Kugler, Benjamin A; Csikos, Vivien; Birky, Cole J; Gilmore, Caleb A; Wenger, Madi; Franczak, Edziu; Davis, Xin; Hauger, Brittany M; Allen, Julie A; Troutwine, Benjamin R; Gonzalez-Duran, Laura; McCoin, Colin S; Chauhan, Munish; Harris, Janna L; Frazier, Alexandria L; Winter, Michelle K; Koch, Lauren G; Britton, Steven L; Thyfault, John P; Wilkins, Heather M

APOE4 drives widespread changes to the hepatic proteome and alters metabolic function.

APOE4 驱动肝脏蛋白质组发生广泛变化,并改变代谢功能。

Lysaker Colton R, Johnson Chelsea N, Csikos Vivien, Franczak Edziu, Tetlow Ashley L, Benson Maggie, Thyfault John P, Geiger Paige C, Morris Jill K, Wilkins Heather M

Trajectories of Response Inhibition Development in Adolescence

青少年时期反应抑制能力发展的轨迹

Zhu, Junda; Smith, Colton R; Garin, Clément M; Zhou, Xin Maizie; Calabro, Finnegan J; Luna, Beatriz; Constantinidis, Christos

AIMP3 maintains cardiac homeostasis by regulating the editing activity of methionyl-tRNA synthetase

AIMP3通过调节甲硫氨酰tRNA合成酶的编辑活性来维持心脏稳态。

Anindhya S Das,Charles P Rabolli,Colton R Martens,Han-Kai Jiang,Yingshen Zhang,Aubree A Zimmer,Kevin Lin,Kedryn K Baskin,Juan D Alfonzo,Federica Accornero

APOE4 Exerts Partial Diet-dependent Effects on Energy Expenditure and Skeletal Muscle Mitochondrial Pathways in a Preclinical Model.

在临床前模型中,APOE4 对能量消耗和骨骼肌线粒体通路产生部分饮食依赖性影响

Johnson Chelsea N, Lysaker Colton R, Gast Elaine C, McCoin Colin S, Kemna Riley E, Fuller Kelly N Z, Kugler Benjamin A, Franczak Edziu, Csikos Vivien, Allen Julie, John Casey S, Wolf MaryJane A, Morris Matthew E, Thyfault John P, Wilkins Heather M, Geiger Paige C, Morris Jill K

Real-time quantification of soluble tartrate-resistant acid phosphatase as a measure of osteoclastogenesis

实时定量可溶性抗酒石酸酸性磷酸酶作为破骨细胞生成的指标

Roosma, Justin A; Gafar, Hammed; Boruff, Maxwell T; Quinn, Colton R; Ashley, Jason W

Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.

蛋白质组学和代谢组学分析揭示了 APOE4 依赖性的全脑、神经元和星形胶质细胞线粒体功能和糖酵解的变化

Lysaker Colton R, Johnson Chelsea N, Csikos Vivien, Franczak Edziu, Benson Maggie, Gilmore Caleb A, Birky Cole J, Davis Xin, McCoin Colin S, Smith Keith P, Puchalska Patrycja, Crawford Peter, Slawson Chad, Thyfault John P, Geiger Paige C, Morris Jill K, Wilkins Heather M

Inhibiting mtDNA transcript translation alters Alzheimer's disease-associated biology

抑制线粒体DNA转录本翻译会改变阿尔茨海默病相关的生物学特性。

Alexander P Gabrielli ,Lesya Novikova ,Amol Ranjan ,Xiaowan Wang ,Nicholas J Ernst ,Dhanushki Abeykoon ,Anysja Roberts ,Annie Kopp ,Clayton Mansel ,Linlan Qiao ,Colton R Lysaker ,Ian W Wiedling ,Heather M Wilkins ,Russell H Swerdlow

Intrinsic aerobic capacity modulates Alzheimer's disease pathological hallmarks, brain mitochondrial function and proteome during aging

内在有氧能力在衰老过程中调节阿尔茨海默病病理特征、脑线粒体功能和蛋白质组。

Kugler, Benjamin A; Lysaker, Colton R; Franczak, Edziu; Hauger, Brittany M; Csikos, Vivien; Stopperan, Julia A; Allen, Julie A; Stanford, John A; Koch, Lauren G; Britton, Steven L; Thyfault, John P; Wilkins, Heather M

Skeletal muscle proteome differs between young APOE3 and APOE4 targeted replacement mice in a sex-dependent manner

APOE3 和 APOE4 靶向替代小鼠之间的骨骼肌蛋白质组存在性别依赖性差异

Chelsea N Johnson, Colton R Lysaker, Colin S McCoin, Mara R Evans, John P Thyfault, Heather M Wilkins, Jill K Morris #, Paige C Geiger #