Genetically engineered cancer models, but not xenografts, faithfully predict anticancer drug exposure in melanoma tumors
基因工程癌症模型(而非异种移植模型)能够准确预测黑色素瘤肿瘤中抗癌药物的暴露情况。
期刊:Oncologist
影响因子:4.2
doi:10.1634/theoncologist.2012-0274
Combest, Austin J; Roberts, Patrick J; Dillon, Patrick M; Sandison, Katie; Hanna, Suzan K; Ross, Charlene; Habibi, Sohrab; Zamboni, Beth; Müller, Markus; Brunner, Martin; Sharpless, Norman E; Zamboni, William C