日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1, multicenter, open-label study to evaluate the pharmacokinetics, safety, and tolerability of a single dose of rimegepant in children (aged ≥6 to <12 years) with a history of migraine

一项 1 期、多中心、开放标签研究,旨在评估单剂量瑞美吉泮在有偏头痛病史的儿童(年龄 ≥6 岁至 <12 岁)中的药代动力学、安全性和耐受性。

Lim, Chay Ngee; Mo, Gary; Bhardwaj, Rajinder; Comisar, Craig M; Emerson, Beth L; Matschke, Kyle T; Fisniku, Ogert; Bertz, Richard; Croop, Robert; Liu, Jing

Population pharmacokinetic modeling of zavegepant, a calcitonin gene-related peptide receptor antagonist, in healthy adults and patients with migraine

在健康成人和偏头痛患者中,对降钙素基因相关肽受体拮抗剂扎维吉泮进行群体药代动力学建模

Comisar, Craig M; Francis, Jose; Hughes, Jim H; Bhardwaj, Rajinder; Bertz, Richard; Liu, Jing

Population Pharmacokinetic Modeling of the Oral Calcitonin Gene-Related Peptide Receptor Antagonist Rimegepant in Adults

口服降钙素基因相关肽受体拮抗剂瑞美吉泮在成人中的群体药代动力学模型

Comisar, Craig M; Hughes, Jim H; Francis, Jose; Chinda, Yorinao; Sano, Yamato; Muto, Chieko; Neumar, Christine; Bhardwaj, Rajinder; Bertz, Richard; Liu, Jing

Exposure Matching Using Population Pharmacokinetic Modeling and Simulation to Support Rimegepant Dose Selection for Pediatric Patients With Migraine

利用群体药代动力学建模和模拟进行暴露匹配,以支持瑞美吉泮在偏头痛儿科患者中的剂量选择

Comisar, Craig M; Hughes, Jim H; Mo, Gary; Bhardwaj, Rajinder; Jakate, Abhijeet; Lim, Chay Ngee; Liu, Jing

Assessing Clinical Integration of Point-of-Care Ultrasound With an Objective Structured Clinical Examination

利用客观结构化临床考试评估床旁超声的临床整合

Caroline Srisarajivakul-Klein, N; Dong, Jennifer; Mednick, Aron; Holmes, Isaac; Comisar, Lauren; Dembitzer, Anne; Sauthoff, Harald; Janjigian, Michael

Understanding Prognosis: Discrepancy in Prognosis Estimates Between Patients With Cirrhosis and their Hepatologists

了解预后:肝硬化患者及其肝病专家对预后的评估存在差异

Kaplan, Alyson; Comisar, Lauren; Ufere, Nneka N; Jannat-Khah, Deanna; Rosenblatt, Russell; Fortune, Brett; Prigerson, Holly G; Brown, Robert Jr

Outpatient total shoulder arthroplasty in the ambulatory surgery center: a comparison of early complications in patients with and without glenoid bone loss

在日间手术中心进行全肩关节置换术:肩胛盂骨缺损患者与无肩胛盂骨缺损患者早期并发症的比较

Stephens, Scott P; Decoons, Ryan M; Szerlip, Benjamin W; Goubeaux, Craig A; Schuette, Hayden B; Glazier, Matthew T; Braden, Abigail M; Hendrickson, Luke A; Comisar, Bruce R

Ceftazidime-Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

头孢他啶-阿维巴坦人群药代动力学模型及成人适应症和患者亚组的药效学目标达成情况

Li, Jianguo; Lovern, Mark; Green, Michelle L; Chiu, Joannellyn; Zhou, Diansong; Comisar, Craig; Xiong, Yuan; Hing, Jeremy; MacPherson, Merran; Wright, James G; Riccobene, Todd; Carrothers, Timothy J; Das, Shampa

Identification of ovarian cancer metastatic miRNAs

卵巢癌转移性 miRNA 的鉴定

Souriya Vang, Hsin-Ta Wu, Andrew Fischer, Daniel H Miller, Shannon MacLaughlan, Elijah Douglass, Lauren Comisar, Margaret Steinhoff, Colin Collins, Peter J S Smith, Laurent Brard, Alexander S Brodsky

Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study

在一项首次人体试验中,对健康受试者进行人源抗IL-6单克隆抗体(sirukumab)的药代动力学、药效学和安全性研究

Xu, Zhenhua; Bouman-Thio, Esther; Comisar, Craig; Frederick, Bart; Van Hartingsveldt, Bart; Marini, Joseph C; Davis, Hugh M; Zhou, Honghui