日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An improved synthesis of Compound 11, a unique bicyclic melanocortin-3 antagonist

化合物 11 的改进合成,化合物 11 是一种独特的双环黑皮质素-3 拮抗剂

Joy, Stephen T; Dahir, Naima S; Cone, Roger D; Mapp, Anna K

Subthreshold activation of the melanocortin system causes generalized sensitization to anorectic agents in mice

黑皮质素系统的阈下激活会导致小鼠对厌食剂产生普遍的敏感性。

Dahir, Naima S; Gui, Yijun; Wu, Yanan; Sweeney, Patrick R; Rouault, Alix Aj; Williams, Savannah Y; Gimenez, Luis E; Sawyer, Tomi K; Joy, Stephen T; Mapp, Anna K; Cone, Roger D

Structure of the Ion Channel Kir7.1 and Implications for its Function in Normal and Pathophysiologic States

Kir7.1离子通道的结构及其在正常和病理生理状态下的功能意义

Peisley, Alys; Hernandez, Ciria C; Dahir, Naima S; Koepping, Laura; Raczkowski, Ashleigh; Su, Min; Ghamari-Langroudi, Masoud; Ji, Xinrui; Gimenez, Luis E; Cone, Roger D

Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency.

在能量缺乏的情况下,AgRP 神经元中黑皮质素-3 受体的表达是神经元正常激活所必需的

Gui Yijun, Dahir Naima S, Wu Yanan, Downing Griffin, Sweeney Patrick, Cone Roger D

The unique structural characteristics of the Kir 7.1 inward rectifier potassium channel: a novel player in energy homeostasis control

Kir 7.1 内向整流钾通道独特的结构特征:能量稳态调控中的新角色

Hernandez, Ciria C; Gimenez, Luis E; Dahir, Naima S; Peisley, Alys; Cone, Roger D

Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents

黑皮质素-3受体(MC3R)的抑制会导致对厌食剂的普遍敏感性增加。

Dahir, Naima S; Gui, Yijun; Wu, Yanan; Sweeney, Patrick R; Williams, Savannah Y; Gimenez, Luis E; Sawyer, Tomi K; Joy, Stephen T; Mapp, Anna K; Cone, Roger D

Demonstration of a Common DPhe(7) to DNal(2')(7) Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides

对黑皮质素-3和黑皮质素-4受体的常见DPhe(7)到DNal(2')(7)肽配体拮抗剂转换的证明,揭示了对黑皮质素肽药理学特性的系统性错误描述

Gimenez, Luis E; Noblin, Terry A; Williams, Savannah Y; Mullick Bagchi, Satarupa; Ji, Ren-Lei; Tao, Ya-Xiong; Jeppesen, Claus B; Conde-Frieboes, Kilian W; Sawyer, Tomi K; Grieco, Paolo; Cone, Roger D

Common Genetic Variation and Age of Onset of Anorexia Nervosa

常见遗传变异与神经性厌食症的发病年龄

Watson, Hunna J; Thornton, Laura M; Yilmaz, Zeynep; Baker, Jessica H; Coleman, Jonathan R I; Adan, Roger A H; Alfredsson, Lars; Andreassen, Ole A; Ask, Helga; Berrettini, Wade H; Boehnke, Michael; Boehm, Ilka; Boni, Claudette; Buehren, Katharina; Bulant, Josef; Burghardt, Roland; Chang, Xiao; Cichon, Sven; Cone, Roger D; Courtet, Philippe; Crow, Scott; Crowley, James J; Danner, Unna N; de Zwaan, Martina; Dedoussis, George; DeSocio, Janiece E; Dick, Danielle M; Dikeos, Dimitris; Dina, Christian; Djurovic, Srdjan; Dmitrzak-Weglarz, Monika; Docampo-Martinez, Elisa; Duriez, Philibert; Egberts, Karin; Ehrlich, Stefan; Eriksson, Johan G; Escaramís, Geòrgia; Esko, Tõnu; Estivill, Xavier; Farmer, Anne; Fernández-Aranda, Fernando; Fichter, Manfred M; Föcker, Manuel; Foretova, Lenka; Forstner, Andreas J; Frei, Oleksandr; Gallinger, Steven; Giegling, Ina; Giuranna, Johanna; Gonidakis, Fragiskos; Gorwood, Philip; Gratacòs, Mònica; Guillaume, Sébastien; Guo, Yiran; Hakonarson, Hakon; Hauser, Joanna; Havdahl, Alexandra; Hebebrand, Johannes; Helder, Sietske G; Herms, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Hinney, Anke; Hübel, Christopher; Hudson, James I; Imgart, Hartmut; Jamain, Stephanie; Janout, Vladimir; Jiménez-Murcia, Susana; Jones, Ian R; Julià, Antonio; Kalsi, Gursharan; Kaminská, Deborah; Kaprio, Jaakko; Karhunen, Leila; Kas, Martien J H; Keel, Pamela K; Kennedy, James L; Keski-Rahkonen, Anna; Kiezebrink, Kirsty; Klareskog, Lars; Klump, Kelly L; Knudsen, Gun Peggy S; La Via, Maria C; Le Hellard, Stephanie; Leboyer, Marion; Li, Dong; Lilenfeld, Lisa; Lin, Bochao; Lissowska, Jolanta; Luykx, Jurjen; Magistretti, Pierre; Maj, Mario; Marsal, Sara; Marshall, Christian R; Mattingsdal, Morten; Meulenbelt, Ingrid; Micali, Nadia; Mitchell, Karen S; Monteleone, Alessio Maria; Monteleone, Palmiero; Myers, Richard; Navratilova, Marie; Ntalla, Ionna; O'Toole, Julie K; Ophoff, Roel A; Padyukov, Leonid; Pantel, Jacques; Papežová, Hana; Pinto, Dalila; Raevuori, Anu; Ramoz, Nicolas; Reichborn-Kjennerud, Ted; Ricca, Valdo; Ripatti, Samuli; Ripke, Stephan; Ritschel, Franziska; Roberts, Marion; Rotondo, Alessandro; Rujescu, Dan; Rybakowski, Filip; Scherag, André; Scherer, Stephen W; Schmidt, Ulrike; Scott, Laura J; Seitz, Jochen; Silén, Yasmina; Šlachtová, Lenka; Slagboom, P Eline; Slof-Op 't Landt, Margarita C T; Slopien, Agnieszka; Sorbi, Sandro; Świątkowska, Beata; Tortorella, Alfonso; Tozzi, Federica; Treasure, Janet; Tsitsika, Artemis; Tyszkiewicz-Nwafor, Marta; Tziouvas, Konstantinos; van Elburg, Annemarie A; van Furth, Eric F; Walton, Esther; Widen, Elisabeth; Zerwas, Stephanie; Zipfel, Stephan; Bergen, Andrew W; Boden, Joseph M; Brandt, Harry; Crawford, Steven; Halmi, Katherine A; Horwood, L John; Johnson, Craig; Kaplan, Allan S; Kaye, Walter H; Mitchell, James E; Olsen, Catherine M; Pearson, John F; Pedersen, Nancy L; Strober, Michael; Werge, Thomas; Whiteman, David C; Woodside, D Blake; Gordon, Scott; Maguire, Sarah; Larsen, Janne T; Parker, Richard; Petersen, Liselotte V; Jordan, Jennifer; Kennedy, Martin; Wade, Tracey D; Birgegård, Andreas; Lichtenstein, Paul; Landén, Mikael; Martin, Nicholas G; Mortensen, Preben Bo; Breen, Gerome; Bulik, Cynthia M

Organization of neural systems expressing melanocortin-3 receptors in the mouse brain: Evidence for sexual dimorphism

小鼠脑中表达黑皮质素-3受体的神经系统的组织:性别二态性的证据

Bedenbaugh, Michelle N; Brener, Samantha C; Maldonado, Jose; Lippert, Rachel N; Sweeney, Patrick; Cone, Roger D; Simerly, Richard B

The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia

黑皮质素-3受体是调节厌食症的药理学靶点

Sweeney, Patrick; Bedenbaugh, Michelle N; Maldonado, Jose; Pan, Pauline; Fowler, Katelyn; Williams, Savannah Y; Gimenez, Luis E; Ghamari-Langroudi, Masoud; Downing, Griffin; Gui, Yijun; Hadley, Colleen K; Joy, Stephen T; Mapp, Anna K; Simerly, Richard B; Cone, Roger D