日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI

保守的细菌核糖体RNA甲基转移酶RsmI识别和修饰30S亚基的机制

Barmada, Mohamed I; McGinity, Erin N; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Harris, George M; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L

Design, Synthesis, and Evaluation of Novel Inhibitors of Aminoglycoside-Resistance 16S Ribosomal RNA Methyltransferases

新型氨基糖苷类抗性16S核糖体RNA甲基转移酶抑制剂的设计、合成与评价

Deprez, Benjamin E; Dey, Debayan; Zelinskaya, Natalia; Csatary, Erika E; Yang, Qimin Winnie; Nie, Minhua; Conn, Graeme L; Wuest, William M

Conserved stem-loops of the SARS-CoV-2 5'-UTR activate OAS1

SARS-CoV-2 5'-UTR 的保守茎环结构激活 OAS1

Oviedo, Alejandro; Bair, Camden R; Vasilakopoulos, Alexander P; Regis, Kierra; Vanlnsberghe, David; Lowen, Anice C; Conn, Graeme L

Comparative analysis of flavivirus sfRNA dynamics and secondary structure

黄病毒sfRNA动力学和二级结构的比较分析

Bair, Camden R; VanInsberghe, David; Lowen, Anice C; Conn, Graeme L; Neufeldt, Christopher J

Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia.

显性负性 PSMB10 会破坏免疫蛋白酶体的组装,导致短暂性 T 淋巴细胞减少症。

Ghosh Sujal, Wang Yuqin, Schultheiss Christoph, Borkhardt Arndt, Dafun Angelique Sanchez, Knipp Liisa, Marwitz Sebastian, Ehl Stephan, Soulard Clara, Haddad Elie, Dey Debayan, Evans Grace, Golwala Zainab M, Bennstein Sabrina B, Laws Hans-Jürgen, Rohlfs Meino, Magg Thomas, Binder Mascha, Kreins Alexandra Y, Bousquet Marie-Pierre, Marcoux Julien, Klein Christoph, Conn Graeme L, Meiners Silke, Hauck Fabian

Basis for selective drug evasion of an aminoglycoside-resistance ribosomal RNA modification.

选择性逃避氨基糖苷类抗性核糖体RNA修饰的基础

Dey Debayan, Mattingly Jacob M, Zelinskaya Natalia, Dunham Christine M, Conn Graeme L

Distant ribose 2'-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface

23S rRNA 69号螺旋的远端核糖2'-O-甲基化预先调控了核糖体亚基界面处的卷曲霉素药物结合口袋。

Nandi, Suparno; Dey, Debayan; Srinivas, Pooja; Dunham, Christine M; Conn, Graeme L

Regulation, structure, and activity of the Pseudomonas aeruginosa MexXY efflux system

铜绿假单胞菌MexXY外排系统的调控、结构和活性

Kavanaugh, Logan G; Hinrichsen, Megan E; Dunham, Christine M; Conn, Graeme L

Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes

在主要外排基因敲除系统中测定铜绿假单胞菌 MexXY-OprM 底物谱,揭示了不同的抗生素底物类别

Kavanaugh, Logan G; Hariharan, Shraddha M; Conn, Graeme L

Discovery of First-in-Class Inhibitors Targeting a Pathogen-Associated Aminoglycoside-Resistance 16S rRNA Methyltransferase

发现靶向病原体相关氨基糖苷类耐药性16S rRNA甲基转移酶的首创抑制剂

Dey, Debayan; Deprez, Benjamin E; Zelinskaya, Natalia; Castro, Jose M; Wuest, William M; Conn, Graeme L