日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study

Xaluritamig,一种针对转移性去势抵抗性前列腺癌的STEAP1 × CD3 XmAb 2+1免疫疗法:首次人体试验剂量探索结果

Kelly, William K; Danila, Daniel C; Lin, Chia-Chi; Lee, Jae-Lyun; Matsubara, Nobuaki; Ward, Patrick J; Armstrong, Andrew J; Pook, David; Kim, Miso; Dorff, Tanya B; Fischer, Stefanie; Lin, Yung-Chang; Horvath, Lisa G; Sumey, Christopher; Yang, Zhao; Jurida, Gabor; Smith, Kristen M; Connarn, Jamie N; Penny, Hweixian L; Stieglmaier, Julia; Appleman, Leonard J

A novel Bayesian generative approach for estimating tumor dynamics from published studies

一种基于贝叶斯生成方法的新型方法,用于根据已发表的研究估计肿瘤动态

Pourzanjani, Arya; Modi, Saurabh; Connarn, Jamie; Zhang, Xinwen; Upreti, Vijay; Lin, Chih-Wei; Mehta, Khamir

Characterizing the exposure-response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma

描述idecabtagene vicleucel在复发/难治性多发性骨髓瘤患者中的暴露-反应关系

Connarn, Jamie N; Witjes, Han; van Zutphen-van Geffen, Marielle; de Greef, Rik; Campbell, Timothy B; Hege, Kristen; Zhou, Simon; Lamba, Manisha

CC-99677, a novel, oral, selective covalent MK2 inhibitor, sustainably reduces pro-inflammatory cytokine production

CC-99677 是一种新型口服选择性共价 MK2 抑制剂,可持续减少促炎细胞因子的产生

Rajula Gaur #, Kofi A Mensah #, Jason Stricker, Mary Adams, Anastasia Parton, Dorota Cedzik, Jamie Connarn, Michael Thomas, Gerald Horan, Peter Schafer, Stuart Mair, Maria Palmisano, Francisco Ramírez-Valle

Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors

组蛋白去乙酰化酶 6 抑制剂 Citarinostat 与紫杉醇联合治疗晚期实体瘤患者的 Ib 期研究

Michael S Gordon, Geoffrey I Shapiro, John Sarantopoulos, Dejan Juric, Brian Lu, Angeliki Zarotiadou, Jamie N Connarn, Yvan Le Bruchec, Calin Dan Dumitru, R Donald Harvey

Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification

索他西普的安全性和对血红蛋白、骨骼和血管钙化的影响

Coyne, Daniel W; Singh, Hem N; Smith, William T; Giuseppi, Ana Carolina; Connarn, Jamie N; Sherman, Matthew L; Dellanna, Frank; Malluche, Hartmut H; Hruska, Keith A

Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment.

enasidenib 治疗期间内源性 CYP3A 诱导标志物 4β-羟基胆固醇的建模和模拟

Li Yan, Connarn Jamie N, Chen Jian, Tong Zeen, Palmisano Maria, Zhou Simon

Identification of non-reported bupropion metabolites in human plasma

人血浆中未报告的安非他酮代谢物的鉴定

Connarn, Jamie N; Luo, Ruijuan; Windak, Jim; Zhang, Xinyuan; Babiskin, Andrew; Kelly, Marisa; Harrington, Gloria; Ellingrod, Vicki L; Kamali, Masoud; McInnis, Melvin; Sun, Duxin

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

PTEN 缺陷型曲妥珠单抗耐药乳腺癌上皮-间质转化过程中的新型癌症干细胞靶点

Lichao Sun, Joseph Burnett, Mari Gasparyan, Fangying Xu, Hui Jiang, Chang-Ching Lin, Ila Myers, Hasan Korkaya, Yajing Liu, Jamie Connarn, Huining He, Ning Zhang, Max S Wicha, Duxin Sun

Metabolism of bupropion by carbonyl reductases in liver and intestine

安非他酮在肝脏和肠道中通过羰基还原酶代谢

Jamie N Connarn, Xinyuan Zhang, Andrew Babiskin, Duxin Sun