日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrated stress response inhibition prolongs the lifespan of a Pelizaeus-Merzbacher disease mouse model by increasing oligodendrocyte survival.

整合应激反应抑制通过增加少突胶质细胞的存活率来延长佩利措伊斯-梅尔茨巴赫病小鼠模型的寿命。

Chen Yanan, Kunjamma Rejani B, Lin Karin, Kai Li, Dima Maria, Bruce Kody, Steckler Ian, Che Young Hyun, Chan-Zervas Jason, Eugenin von Bernhardi Jaime, Connelly Caitlin, Ece Sude, Newell Grace, Bergles Dwight E, Sidrauski Carmela, Popko Brian

Chronic integrated stress response causes dysregulated cholesterol synthesis in white matter disease

慢性整合应激反应导致白质疾病中胆固醇合成失调。

Lin, Karin; Ly, Nina; Kunjamma, Rejani B; Vu, Ngoc; King, Bryan; Robb, Holly M; Mohler, Eric G; Sridar, Janani; Hao, Qi; Zavala-Solorio, José; Zhang, Chunlian; Shahryari, Varahram; van Bruggen, Nick; Connelly, Caitlin F; Bennett, Bryson D; Lee, James J; Sidrauski, Carmela

GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system

GDF15是中枢神经系统综合应激反应的动态生物标志物。

Asundi, Jyoti; Zhang, Chunlian; Donnelly-Roberts, Diana; Solorio, Josè Zavala; Challagundla, Malleswari; Connelly, Caitlin; Boch, Christina; Chen, Jun; Richter, Mario; Maneshi, Mohammad Mehdi; Swensen, Andrew M; Lebon, Lauren; Schiffmann, Raphael; Sanyal, Subhabrata; Sidrauski, Carmela; Kolumam, Ganesh; Baruch, Amos

Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.

蛋白激酶 R 和整合应激反应驱动由 RNA 脱氨酶 ADAR1 突变引起的免疫病理

Maurano Megan, Snyder Jessica M, Connelly Caitlin, Henao-Mejia Jorge, Sidrauski Carmela, Stetson Daniel B

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

对10万个人类癌症基因组的分析揭示了肿瘤突变负荷的概况

Chalmers, Zachary R; Connelly, Caitlin F; Fabrizio, David; Gay, Laurie; Ali, Siraj M; Ennis, Riley; Schrock, Alexa; Campbell, Brittany; Shlien, Adam; Chmielecki, Juliann; Huang, Franklin; He, Yuting; Sun, James; Tabori, Uri; Kennedy, Mark; Lieber, Daniel S; Roels, Steven; White, Jared; Otto, Geoffrey A; Ross, Jeffrey S; Garraway, Levi; Miller, Vincent A; Stephens, Phillip J; Frampton, Garrett M

Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast

整合表型组学揭示了出芽酵母表型多样性的结构

Skelly, Daniel A; Merrihew, Gennifer E; Riffle, Michael; Connelly, Caitlin F; Kerr, Emily O; Johansson, Marnie; Jaschob, Daniel; Graczyk, Beth; Shulman, Nicholas J; Wakefield, Jon; Cooper, Sara J; Fields, Stanley; Noble, William S; Muller, Eric G D; Davis, Trisha N; Dunham, Maitreya J; Maccoss, Michael J; Akey, Joshua M

Population genomics and transcriptional consequences of regulatory motif variation in globally diverse Saccharomyces cerevisiae strains

全球多样化酿酒酵母菌株中调控基序变异的群体基因组学和转录后果

Connelly, Caitlin F; Skelly, Daniel A; Dunham, Maitreya J; Akey, Joshua M

On the prospects of whole-genome association mapping in Saccharomyces cerevisiae

关于酿酒酵母全基因组关联作图的前景

Connelly, Caitlin F; Akey, Joshua M

Highly punctuated patterns of population structure on the X chromosome and implications for African evolutionary history

X染色体上人口结构的高度间断模式及其对非洲进化史的影响

Lambert, Charla A; Connelly, Caitlin F; Madeoy, Jennifer; Qiu, Ruolan; Olson, Maynard V; Akey, Joshua M

Population genomic analysis of ALMS1 in humans reveals a surprisingly complex evolutionary history

对人类ALMS1基因的群体基因组分析揭示了其出人意料的复杂进化史。

Scheinfeldt, Laura B; Biswas, Shameek; Madeoy, Jennifer; Connelly, Caitlin F; Schadt, Eric E; Akey, Joshua M