日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

Nub1 捕获未折叠的 FAT10,通过 26S 蛋白酶体进行不依赖泛素的降解

Connor Arkinson, Ken C Dong, Christine L Gee, Shawn M Costello, Susan Marqusee, Andreas Martin

Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1

使用 UBIMAX 分析泛素信号传导,揭示了 DNA 损伤和 SCFβ-Trcp1 依赖的肌动蛋白组织蛋白 Dbn1 泛素化

Camilla S Colding-Christensen #, Ellen S Kakulidis #, Javier Arroyo-Gomez, Ivo A Hendriks, Connor Arkinson, Zita Fábián, Agnieszka Gambus, Niels Mailand, Julien P Duxin, Michael L Nielsen

Preparation of site-specifically fluorophore-labeled polyubiquitin chains for FRET studies of Cdc48 substrate processing

制备位点特异性荧光标记的多泛素链,用于 Cdc48 底物加工的 FRET 研究

Cameron Williams, Ken C Dong, Connor Arkinson, Andreas Martin

Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site

Cryo-EM 揭示了通过隐秘结合位点抑制 USP1 的机制

Martin L Rennie, Connor Arkinson, Viduth K Chaugule, Helen Walden

Allosteric mechanism for site-specific ubiquitination of FANCD2

FANCD2 位点特异性泛素化的变构机制

Viduth K Chaugule, Connor Arkinson, Martin L Rennie, Outi Kämäräinen, Rachel Toth, Helen Walden

Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA

FANCI 和 FANCD2 泛素化的差异功能稳定 DNA 上的 ID2 复合物

Martin L Rennie, Kimon Lemonidis, Connor Arkinson, Viduth K Chaugule, Mairi Clarke, James Streetley, Laura Spagnolo, Helen Walden

Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1

单泛素化 FANCD2 去泛素化的特异性由 USP1 的 N 端驱动

Connor Arkinson, Viduth K Chaugule, Rachel Toth, Helen Walden