The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression
多态性变异 rs1800734 影响 MLH1 启动子中的甲基化获取和等位基因特异性 TFAP4 结合，导致差异 mRNA 表达
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-019-49952-x
Rachael Thomas, Davide Trapani, Lily Goodyer-Sait, Marketa Tomkova, Ceres Fernandez-Rozadilla, Nora Sahnane, Connor Woolley, Hayley Davis, Laura Chegwidden, Skirmantas Kriaucionis, Timothy Maughan, Simon Leedham, Claire Palles, Daniela Furlan, Ian Tomlinson, Annabelle Lewis1
