日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms

NLRP3诱导的全身性炎症控制JAK2V617F突变型骨髓增生性肿瘤的发展

Ruth-Miriam Koerber ,Calvin Krollmann ,Kevin Cieslak ,Elisabeth Tregel ,Maria L Saenz ,Tim H Brümmendorf ,Steffen Koschmieder ,Martin Griesshammer ,Ines Gütgemann ,Conny K Baldauf ,Thomas Fischer ,Peter Brossart ,Carl Christian Kolbe ,Eicke Latz ,Dominik Wolf # ,Lino L Teichmann #

Activation of integrin signaling up-regulates pro-inflammatory cytokines in JAK2-V617F positive hematopoietic cells

整合素信号通路的激活可上调JAK2-V617F阳性造血细胞中的促炎细胞因子。

Baldauf, Conny K; Fahldieck, Corinna; Angenstein, Alexa; Weinert, Sönke; Hakobyan, Mariam; Lipka, Daniel B; Haage, Tobias R; Bhuria, Vikas; Böttcher, Martin; Mougiakakos, Dimitrios; Schraven, Burkhart; Fischer, Thomas

Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia.

中性粒细胞特异性表达 JAK2-V617F 或 CALRmut 可诱导骨髓增生性肿瘤中出现不同的炎症特征

Haage Tobias Ronny, Charakopoulos Emmanouil, Bhuria Vikas, Baldauf Conny K, Korthals Mark, Handschuh Juliane, Müller Peter, Li Juan, Harit Kunjan, Nishanth Gopala, Frey Stephanie, Böttcher Martin, Fischer Klaus-Dieter, Dudeck Jan, Dudeck Anne, Lipka Daniel B, Schraven Burkhart, Green Anthony R, Müller Andreas J, Mougiakakos Dimitrios, Fischer Thomas

Genetic Knock-out of TNFR1 and TNFR2 in a JAK2-V617F Polycythemia Vera Mouse Model

在JAK2-V617F真性红细胞增多症小鼠模型中进行TNFR1和TNFR2基因敲除

Müller, Peter; Baldauf, Conny K; Haage, Tobias R; Charakopoulos, Emmanouil; Böttcher, Martin; Bhuria, Vikas; Mougiakakos, Dimitrios; Schraven, Burkhart; Fischer, Thomas

Anti-IL-6 cytokine treatment has no impact on elevated hematocrit or splenomegaly in a polycythemia vera mouse model

在真性红细胞增多症小鼠模型中,抗IL-6细胞因子治疗对血细胞比容升高或脾肿大没有影响。

Baldauf, Conny K; Müller, Peter; Haage, Tobias R; Adam-Frey, Stephanie; Lokau, Juliane; Garbers, Christoph; Fischer, Thomas

Thromboinflammation in Myeloproliferative Neoplasms (MPN)-A Puzzle Still to Be Solved

骨髓增生性肿瘤(MPN)中的血栓炎症——一个尚未解开的谜题

Bhuria, Vikas; Baldauf, Conny K; Schraven, Burkhart; Fischer, Thomas

Anti-inflammatory treatment in MPN: targeting TNFR1 and TNFR2 in JAK2-V617F-induced disease

MPN的抗炎治疗:靶向JAK2-V617F诱导疾病中的TNFR1和TNFR2

Müller, Peter; Baldauf, Conny K; Haage, Tobias R; Waldleben, Ana M; Richter, Fabian; Pfizenmaier, Klaus; Fischer, Thomas