日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

白细胞介素-4激活的巨噬细胞通过维持CCR3依赖性嗜酸性粒细胞增多症来介导对丝虫感染的免疫力

Turner Joseph D, Pionnier Nicolas, Furlong-Silva Julio, Sjoberg Hanna, Cross Stephen, Halliday Alice, Guimaraes Ana F, Cook Darren A N, Steven Andrew, Van Rooijen Nico, Allen Judith E, Jenkins Stephen J, Taylor Mark J

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis

阿苯达唑和抗生素具有协同作用,可在丝虫病临床前模型中提供短期抗沃尔巴克氏体治愈性治疗。

Turner, Joseph D; Sharma, Raman; Al Jayoussi, Ghaith; Tyrer, Hayley E; Gamble, Joanne; Hayward, Laura; Priestley, Richard S; Murphy, Emma A; Davies, Jill; Waterhouse, David; Cook, Darren A N; Clare, Rachel H; Cassidy, Andrew; Steven, Andrew; Johnston, Kelly L; McCall, John; Ford, Louise; Hemingway, Janet; Ward, Stephen A; Taylor, Mark J

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis

短期高剂量利福平治疗可使沃尔巴克氏体耗竭,这可预测淋巴丝虫病和盘尾丝虫病临床前模型的治愈结果。

Aljayyoussi, Ghaith; Tyrer, Hayley E; Ford, Louise; Sjoberg, Hanna; Pionnier, Nicolas; Waterhouse, David; Davies, Jill; Gamble, Joanne; Metuge, Haelly; Cook, Darren A N; Steven, Andrew; Sharma, Raman; Guimaraes, Ana F; Clare, Rachel H; Cassidy, Andrew; Johnston, Kelly L; Myhill, Laura; Hayward, Laura; Wanji, Samuel; Turner, Joseph D; Taylor, Mark J; Ward, Stephen A

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis

米诺环素作为一种重新利用的抗沃尔巴克氏体成虫杀灭剂:在人淋巴丝虫病小鼠感染模型中优于多西环素方案。

Sharma, Raman; Al Jayoussi, Ghaith; Tyrer, Hayley E; Gamble, Joanne; Hayward, Laura; Guimaraes, Ana F; Davies, Jill; Waterhouse, David; Cook, Darren A N; Myhill, Laura J; Clare, Rachel H; Cassidy, Andrew; Steven, Andrew; Johnston, Kelly L; Ford, Louise; Turner, Joseph D; Ward, Stephen A; Taylor, Mark J

Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms

蛇毒成分中具有医学意义的差异是由不同的基因组后机制决定的。

Casewell, Nicholas R; Wagstaff, Simon C; Wüster, Wolfgang; Cook, Darren A N; Bolton, Fiona M S; King, Sarah I; Pla, Davinia; Sanz, Libia; Calvete, Juan J; Harrison, Robert A

Autophagy regulates Wolbachia populations across diverse symbiotic associations

自噬在多种共生关系中调节沃尔巴克氏体种群

Voronin, Denis; Cook, Darren A N; Steven, Andrew; Taylor, Mark J