日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preventing surgery-induced natural killer cell suppression and metastases by inhibiting PI3K-gamma signaling in myeloid-derived suppressor cells.

通过抑制髓系来源抑制细胞中的 PI3K-γ 信号传导,防止手术引起的自然杀伤细胞抑制和转移。

Angka Leonard, Tennakoon Gayashan, Cook David P, Martel Andre B, Market Marisa, Tanese de Souza Christiano, Cummins Emma, Samudio Ismael, Kekre Natasha, Ardolino Michele, Vanderhyden Barbara C, Kennedy Michael A, Auer Rebecca C

Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.

胰腺导管腺癌分支类器官模型中异质性驱动的表型可塑性和治疗反应

Papargyriou Aristeidis, Najajreh Mulham, Cook David P, Maurer Carlo H, Bärthel Stefanie, Messal Hendrik A, Ravichandran Sakthi K, Richter Till, Knolle Moritz, Metzler Thomas, Shastri Akul R, Öllinger Rupert, Jasper Jacob, Schmidleitner Laura, Wang Surui, Schneeweis Christian, Ishikawa-Ankerhold Hellen, Engleitner Thomas, Mataite Laura, Semina Mariia, Trabulssi Hussein, Lange Sebastian, Ravichandra Aashreya, Schuster Maximilian, Mueller Sebastian, Peschke Katja, Schäfer Arlett, Dobiasch Sophie, Combs Stephanie E, Schmid Roland M, Bausch Andreas R, Braren Rickmer, Heid Irina, Scheel Christina H, Schneider Günter, Zeigerer Anja, Luecken Malte D, Steiger Katja, Kaissis Georgios, van Rheenen Jacco, Theis Fabian J, Saur Dieter, Rad Roland, Reichert Maximilian

Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension

绘制肺动脉高压发展过程中导致闭塞性动脉重塑的疾病特异性血管细胞群图谱

Cober, Nicholas D; McCourt, Emma; Godoy, Rafael Soares; Deng, Yupu; Schlosser, Ken; Qamsari, Elmira Safaie; Azami, Jalil; Salehisiavashani, Elham; Cook, David P; Lemay, Sarah-Eve; Klouda, Timothy; Yuan, Ke; Bonnet, Sébastien; Stewart, Duncan J

Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.

转谷氨酰胺酶 2 通过调节免疫微环境来调控卵巢癌转移

Ibrahim Dalia, Grondin Melanie, Galpin Kristianne, Asif Sara, Thompson Emily, Nersesian Sarah, Abou-Hamad John, Echaibi Maryam, Rodriguez Galaxia M, Navals Pauline, Macdonald Elizabeth, Ryan Brianna, Cook David P, Keillor Jeffrey W, Vanderhyden Barbara C

Mesenchymal ovarian cancer cells promote CD8(+) T cell exhaustion through the LGALS3-LAG3 axis.

间质性卵巢癌细胞通过 LGALS3-LAG3 轴促进 CD8(+) T 细胞耗竭

Yakubovich Edward, Cook David P, Rodriguez Galaxia M, Vanderhyden Barbara C

Transcriptional census of epithelial-mesenchymal plasticity in cancer

癌症中上皮-间质可塑性的转录组普查

Cook, David P; Vanderhyden, Barbara C

Single-Cell RNA Sequencing-Based Characterization of Resident Lung Mesenchymal Stromal Cells in Bronchopulmonary Dysplasia

基于单细胞RNA测序的支气管肺发育不良中肺间充质基质细胞的表征

Mižíková, Ivana; Lesage, Flore; Cyr-Depauw, Chanele; Cook, David P; Hurskainen, Maria; Hänninen, Satu M; Vadivel, Arul; Bardin, Pauline; Zhong, Shumei; Carpén, Olli; Vanderhyden, Barbara C; Thébaud, Bernard

The Tumor Immune Profile of Murine Ovarian Cancer Models: An Essential Tool For Ovarian Cancer Immunotherapy Research.

小鼠卵巢癌模型的肿瘤免疫特征:卵巢癌免疫治疗研究的重要工具

Rodriguez Galaxia M, Galpin Kristianne J C, Cook David P, Yakubovich Edward, Maranda Vincent, Macdonald Elizabeth A, Wilson-Sanchez Juliette, Thomas Anjali L, Burdette Joanna E, Vanderhyden Barbara C

Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma

鉴定促进胶质母细胞瘤中Lgl1磷酸化的Rac鸟嘌呤核苷酸交换因子

Lavictoire, Sylvie J; Jomaa, Danny; Gont, Alexander; Jardine, Karen; Cook, David P; Lorimer, Ian A J

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

开发和应用高通量筛选来发现破坏 ErbB4 信号传导的化合物:候选癌症治疗药物

Richard L Cullum, Lauren M Lucas, Jared I Senfeld, John T Piazza, Logan T Neel, Kanupriya Whig, Ling Zhai, Mackenzie H Harris, Cristina C Rael, Darby C Taylor, Laura J Cook, David P Kaufmann, Christopher P Mill, Megan A Jacobi, Forrest T Smith, Mark Suto, Robert Bostwick, Ram B Gupta, Allan E David,