日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Navitoclax acts synergistically with irradiation to induce apoptosis in preclinical models of H3K27M-altered diffuse midline glioma

在H3K27M突变型弥漫性中线胶质瘤的临床前模型中,Navitoclax与放射治疗具有协同作用,可诱导细胞凋亡。

Vardon, Ashley; Haston, Scott; Hamdi, Hiba; Cooksley, Grace; Guiho, Romain; Carvalho, Diana; Carter, Rebecca; Boult, Jessica Katherine Rowena; Gharai, Daniel; Cloete, Ielyaas; Grey, James; Apps, John; Zhou, Daohong; Zheng, Guangrong; Martínez-Máñez, Ramón; Lythgoe, Mark Francis; Donovan, Laura Kate; Carcaboso, Angel Montero; Williams, Owen; Hong, Ying; Alexandre, Paula; Gil, Jesus; Dean, Jamie Adam; Michod, David; Jones, Chris; Hargrave, Darren; Martinez-Barbera, Juan-Pedro

Proximal cysteine residues in proteins promote N(ε)-carboxyalkylation of lysine residues by α-dicarbonyl compounds.

蛋白质中的近端半胱氨酸残基促进α-二羰基化合物对赖氨酸残基的N(α)-羧烷基化

Panja Sudipta, Rankenberg Johanna, Michel Cole, Cooksley Grace, Glomb Marcus A, Nagaraj Ram H