日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis

抑制性先天免疫传感器NLRP12通过调节肠道菌群稳态来维持对抗肥胖的阈值

Agnieszka D Truax ,Liang Chen ,Jason W Tam ,Ning Cheng ,Hao Guo ,A Alicia Koblansky ,Wei-Chun Chou ,Justin E Wilson ,W June Brickey ,Alex Petrucelli ,Rongrong Liu ,Daniel E Cooper ,Mark J Koenigsknecht ,Vincent B Young ,Mihai G Netea ,Rinke Stienstra ,R Balfour Sartor ,Stephanie A Montgomery ,Rosalind A Coleman ,Jenny P-Y Ting

Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype

基因组DNA纳米颗粒可挽救视紫红质相关性视网膜色素变性表型

Han, Zongchao; Banworth, Marcellus J; Makkia, Rasha; Conley, Shannon M; Al-Ubaidi, Muayyad R; Cooper, Mark J; Naash, Muna I

S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA

含S/MAR的DNA纳米颗粒可促进RPE基因的持续表达,并改善RPE65相关的LCA。

Koirala, Adarsha; Makkia, Rasha S; Conley, Shannon M; Cooper, Mark J; Naash, Muna I

DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice

DNA纳米颗粒介导的ABCA4递送可挽救小鼠的Stargardt营养不良症

Han, Zongchao; Conley, Shannon M; Makkia, Rasha S; Cooper, Mark J; Naash, Muna I

Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine.

利用聚乙二醇和聚赖氨酸的 pH 响应嵌段共聚物增强 DNA 纳米颗粒对气道基因转移的促进作用

Boylan Nicholas J, Kim Anthony J, Suk Jung Soo, Adstamongkonkul Pichet, Simons Brian W, Lai Samuel K, Cooper Mark J, Hanes Justin

Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells

纳米颗粒介导的视网膜色素上皮细胞特异性基因转移

Koirala, Adarsha; Makkia, Rasha S; Cooper, Mark J; Naash, Muna I

N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles

N-乙酰半胱氨酸通过高度压缩的DNA纳米颗粒增强囊性纤维化痰液的渗透性和气道基因转移

Suk, Jung Soo; Boylan, Nicholas J; Trehan, Kanika; Tang, Benjamin C; Schneider, Craig S; Lin, Jung-Ming G; Boyle, Michael P; Zeitlin, Pamela L; Lai, Samuel K; Cooper, Mark J; Hanes, Justin

Long-term transgene expression in the central nervous system using DNA nanoparticles

利用DNA纳米颗粒在中枢神经系统中实现转基因的长期表达

Yurek, David M; Fletcher, Anita M; Smith, George M; Seroogy, Kim B; Ziady, Assem G; Molter, Joseph; Kowalczyk, Tomasz H; Padegimas, Linas; Cooper, Mark J

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

利用压缩DNA纳米颗粒对视网膜色素变性模型进行部分结构和功能修复

Cai, Xue; Nash, Zack; Conley, Shannon M; Fliesler, Steven J; Cooper, Mark J; Naash, Muna I

Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina

将压缩的DNA纳米颗粒注入小鼠眼部不会引起视网膜毒性

Ding, Xi-Qin; Quiambao, Alexander B; Fitzgerald, J Browning; Cooper, Mark J; Conley, Shannon M; Naash, Muna I