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Transcriptomic and functional analysis of ANGPTL4 overexpression in pancreatic cancer nominates targets that reverse chemoresistance

胰腺癌中ANGPTL4过表达的转录组学和功能分析揭示了逆转化疗耐药性的靶点

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-023-11010-1

Gordon, Emily R; Wright, Carter A; James, Mikayla; Cooper, Sara J

Characteristics and experiences of patients from a community-based and consumer-directed hereditary cancer population screening initiative

一项以社区为基础、以消费者为主导的遗传性癌症人群筛查计划中患者的特征和经历

期刊:HGG Advances

影响因子:3.6

doi:10.1016/j.xhgg.2021.100055

Greve, Veronica; Odom, Katherine; Pudner, Susanna; Lamb, Neil E; Cooper, Sara J; East, Kelly

A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1

GLUT3在胶质母细胞瘤细胞侵袭中发挥着GLUT1无法重现的作用。

期刊:Cell Adhesion & Migration

影响因子:3.5

doi:10.1080/19336918.2021.1903684

Libby, Catherine J; Gc, Sajina; Benavides, Gloria A; Fisher, Jennifer L; Williford, Sarah E; Zhang, Sixue; Tran, Anh Nhat; Gordon, Emily R; Jones, Amber B; Tuy, Kaysaw; Flavahan, William; Gordillo, Juan; Long, Ashlee; Cooper, Sara J; Lasseigne, Brittany N; Augelli-Szafran, Corinne E; Darley-Usmar, Victor; Hjelmeland, Anita B

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

剖析具有异常多转录因子关联的基因位点的调控活性和序列组成

期刊:Genome Research

影响因子:5.5

doi:10.1101/gr.260463.119

Ramaker, Ryne C; Hardigan, Andrew A; Goh, Say-Tar; Partridge, E Christopher; Wold, Barbara; Cooper, Sara J; Myers, Richard M

信号转导

发表日期：2020

文献求助收藏

Histone deacetylase inhibition promotes intratumoral CD8(+) T-cell responses, sensitizing murine breast tumors to anti-PD1.

组蛋白去乙酰化酶抑制可促进肿瘤内 CD8(+) T 细胞反应，使小鼠乳腺肿瘤对 PD-1 抗体敏感

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-019-02430-9

McCaw Tyler R, Li Mei, Starenki Dmytro, Liu Mingyong, Cooper Sara J, Arend Rebecca C, Forero Andres, Buchsbaum Donald J, Randall Troy D

The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth.

小鼠乳腺肿瘤上 MHC II 类分子的表达可延缓 T 细胞耗竭，扩大 T 细胞库，并减缓肿瘤生长

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-018-2262-5

McCaw Tyler R, Li Mei, Starenki Dmytro, Cooper Sara J, Liu Mingyong, Meza-Perez Selene, Arend Rebecca C, Buchsbaum Donald J, Forero Andres, Randall Troy D

肿瘤

发表日期：2019

文献求助收藏

Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis

染色质结构域解旋酶DNA结合蛋白7在坏死/缺血微环境中受到抑制，并且是胶质母细胞瘤血管生成的新型调节因子

期刊:Stem Cells

影响因子:3.6

doi:10.1002/stem.2969

Boyd, Nathaniel H; Walker, Kiera; Ayokanmbi, Adetokunbo; Gordon, Emily R; Whetsel, Julia; Smith, Cynthia M; Sanchez, Richard G; Lubin, Farah D; Chakraborty, Asmi; Tran, Anh Nhat; Herting, Cameron; Hambardzumyan, Dolores; Yancey Gillespie, G; Hackney, James R; Cooper, Sara J; Jiao, Kai; Hjelmeland, Anita B

Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

高级别浆液性卵巢癌新辅助化疗的分子反应

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-17-0594

Arend, Rebecca C; Londoño, Angelina I; Montgomery, Allison M; Smith, Haller J; Dobbin, Zachary C; Katre, Ashwini A; Martinez, Alba; Yang, Eddy S; Alvarez, Ronald D; Huh, Warner K; Bevis, Kerri S; Straughn, J Michael Jr; Estes, Jacob M; Novak, Lea; Crossman, David K; Cooper, Sara J; Landen, Charles N; Leath, Charles A 3rd

powerTCR: A model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

powerTCR：一种基于模型的T细胞受体库克隆大小分布比较分析方法

期刊:PLoS Computational Biology

影响因子:3.6

doi:10.1371/journal.pcbi.1006571

Koch, Hillary; Starenki, Dmytro; Cooper, Sara J; Myers, Richard M; Li, Qunhua

Novel variant alters splicing of TGFB2 in family with features of Loeys-Dietz syndrome.

新型变异改变了具有 Loeys-Dietz 综合征特征的家族中 TGFB2 的剪接

Transcriptomic and functional analysis of ANGPTL4 overexpression in pancreatic cancer nominates targets that reverse chemoresistance

胰腺癌中ANGPTL4过表达的转录组学和功能分析揭示了逆转化疗耐药性的靶点

Characteristics and experiences of patients from a community-based and consumer-directed hereditary cancer population screening initiative

一项以社区为基础、以消费者为主导的遗传性癌症人群筛查计划中患者的特征和经历

A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1

GLUT3在胶质母细胞瘤细胞侵袭中发挥着GLUT1无法重现的作用。

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

剖析具有异常多转录因子关联的基因位点的调控活性和序列组成

Histone deacetylase inhibition promotes intratumoral CD8(+) T-cell responses, sensitizing murine breast tumors to anti-PD1.

组蛋白去乙酰化酶抑制可促进肿瘤内 CD8(+) T 细胞反应，使小鼠乳腺肿瘤对 PD-1 抗体敏感

The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth.

小鼠乳腺肿瘤上 MHC II 类分子的表达可延缓 T 细胞耗竭，扩大 T 细胞库，并减缓肿瘤生长

Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis

染色质结构域解旋酶DNA结合蛋白7在坏死/缺血微环境中受到抑制，并且是胶质母细胞瘤血管生成的新型调节因子

Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

高级别浆液性卵巢癌新辅助化疗的分子反应

powerTCR: A model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

powerTCR：一种基于模型的T细胞受体库克隆大小分布比较分析方法