日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Safety and Immunogenicity of GTU(®)MultiHIV DNA Vaccine Delivered by Transcutaneous and Intramuscular Injection With or Without Electroporation in HIV-1 Positive Subjects on Suppressive ART

在接受抗逆转录病毒疗法(ART)的HIV-1阳性受试者中,经皮和肌肉注射(伴或不伴电穿孔)递送GTU®MultiHIV DNA疫苗的安全性和免疫原性研究。

Haidari, G; Day, Suzanne; Wood, M; Ridgers, H; Cope, Alethea V; Fleck, Sue; Yan, Celine; Reijonen, Kalevi; Hannaman, Drew; Spentzou, Aggeliki; Hayes, Peter; Vogt, A; Combadiere, Behazine; Cook, Adrian; McCormack, Sheena; Shattock, Robin J

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

HIV疫苗诱导的IgG抗体的包膜特异性识别模式与免疫原结构和序列相关

Nadai, Yuka; Held, Kathrin; Joseph, Sarah; Ahmed, Mohamed I M; Hoffmann, Verena S; Peterhoff, David; Missanga, Marco; Bauer, Asli; Joachim, Agricola; Reimer, Ulf; Zerweck, Johannes; McCormack, Sheena; Cope, Alethea V; Tatoud, Roger; Shattock, Robin J; Robb, Merlin Lee; Sandstroem, Eric G; Hoelscher, Michael; Maboko, Leonard; Bakari, Muhammad; Kroidl, Arne; Wagner, Ralf; Weber, Jonathan; Pollakis, Georgios; Geldmacher, Christof

Acceptability and feasibility study of patient-specific 'tumouroids' as personalised treatment screening tools: Protocol for prospective tissue and data collection of participants with confirmed or suspected renal cell carcinoma

患者特异性“肿瘤样体”作为个性化治疗筛选工具的可接受性和可行性研究:针对确诊或疑似肾细胞癌患者的前瞻性组织和数据收集方案

Tran, Maxine G B; Neves, Joana B; Stamati, Katerina; Redondo, Patricia; Cope, Alethea; Brew-Graves, Chris; Williams, Norman R; Grierson, Jack; Cheema, Umber; Loizidou, Marilena; Emberton, Mark

Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine

皮肤和肌肉DNA联合免疫启动可增强对1型人类免疫缺陷病毒C亚型包膜疫苗的体液免疫反应

Cheeseman, Hannah Mary; Day, Suzanne; McFarlane, Leon Robert; Fleck, Sue; Miller, Aleisha; Cole, Tom; Sousa-Santos, Nelson; Cope, Alethea; Cizmeci, Deniz; Tolazzi, Monica; Hwekwete, Edith; Hannaman, Drew; Kratochvil, Sven; McKay, Paul Francis; Chung, Amy W; Kent, Stephen J; Cook, Adrian; Scarlatti, Gabriella; Abraham, Sonya; Combadiere, Behazine; McCormack, Sheena; Lewis, David John; Shattock, Robin John

Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates

人类免疫缺陷病毒疫苗联合抗逆转录病毒药物预防在感染猴-人类免疫缺陷病毒的非人灵长类动物中表现出更优的疗效

Le Grand, Roger; Dereuddre-Bosquet, Nathalie; Dispinseri, Stefania; Gosse, Leslie; Desjardins, Delphine; Shen, Xiaoying; Tolazzi, Monica; Ochsenbauer, Christina; Saidi, Hela; Tomaras, Georgia; Prague, Mélanie; Barnett, Susan W; Thiebaut, Rodolphe; Cope, Alethea; Scarlatti, Gabriella; Shattock, Robin J

Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study

在女性志愿者中,通过肠外途径和黏膜途径接种HIV-1 gp140疫苗的免疫原性比较;MUCOVAC2,一项随机双中心研究

Cosgrove, Catherine A; Lacey, Charles J; Cope, Alethea V; Bartolf, Angela; Morris, Georgina; Yan, Celine; Baden, Susan; Cole, Tom; Carter, Darrick; Brodnicki, Elizabeth; Shen, Xiaoying; Joseph, Sarah; DeRosa, Stephen C; Peng, Lili; Yu, Xuesong; Ferrari, Guido; Seaman, Mike; Montefiori, David C; Frahm, Nicole; Tomaras, Georgia D; Stöhr, Wolfgang; McCormack, Sheena; Shattock, Robin J

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

疫苗诱导产生的针对猴免疫缺陷病毒SIVmac239包膜的线性表位特异性抗体与非人灵长类动物体内针对人类免疫缺陷病毒1型包膜的抗体不同。

Shen, Xiaoying; Duffy, Ryan; Howington, Robert; Cope, Alethea; Sadagopal, Shanmugalakshmi; Park, Haesun; Pal, Ranajit; Kwa, Suefen; Ding, Song; Yang, Otto O; Fouda, Genevieve G; Le Grand, Roger; Bolton, Diane; Esteban, Mariano; Phogat, Sanjay; Roederer, Mario; Amara, Rama R; Picker, Louis J; Seder, Robert A; McElrath, M Juliana; Barnett, Susan; Permar, Sallie R; Shattock, Robin; DeVico, Anthony L; Felber, Barbara K; Pavlakis, George N; Pantaleo, Giuseppe; Korber, Bette T; Montefiori, David C; Tomaras, Georgia D

Enhanced immunogenicity of an HIV-1 DNA vaccine delivered with electroporation via combined intramuscular and intradermal routes

通过肌内和皮内联合途径,利用电穿孔技术递送的HIV-1 DNA疫苗具有增强的免疫原性

Mann, Jamie F S; McKay, Paul F; Fiserova, Anezka; Klein, Katja; Cope, Alethea; Rogers, Paul; Swales, Julie; Seaman, Michael S; Combadiere, Behazine; Shattock, Robin J

Phase I randomised clinical trial of an HIV-1(CN54), clade C, trimeric envelope vaccine candidate delivered vaginally

一项针对HIV-1(CN54)C亚型三聚体包膜疫苗候选物的阴道给药I期随机临床试验

Lewis, David J; Fraser, Carol A; Mahmoud, Abdel N; Wiggins, Rebecca C; Woodrow, Maria; Cope, Alethea; Cai, Chun; Giemza, Rafaela; Jeffs, Simon A; Manoussaka, Maria; Cole, Tom; Cranage, Martin P; Shattock, Robin J; Lacey, Charles J

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel.

局部预先应用替诺福韦凝胶预防SIV直肠传播和激发猕猴T细胞反应

Cranage Martin, Sharpe Sally, Herrera Carolina, Cope Alethea, Dennis Mike, Berry Neil, Ham Claire, Heeney Jonathan, Rezk Naser, Kashuba Angela, Anton Peter, McGowan Ian, Shattock Robin