日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis

DNAJB6 是神经元对淀粉样变性敏感性的关键因素

Arun Thiruvalluvan, Eduardo P de Mattos, Jeanette F Brunsting, Rob Bakels, Despina Serlidaki, Lara Barazzuol, Paola Conforti, Azra Fatima, Seda Koyuncu, Elena Cattaneo, David Vilchez, Steven Bergink, Erik H W G Boddeke, Sjef Copray, Harm H Kampinga

Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease

人类 A53T α-突触核蛋白对帕金森病细胞模型中的线粒体动力学造成损害以及 NAP(达武奈肽)的挽救作用

T Q Melo, K C van Zomeren, M F R Ferrari, H W G M Boddeke, J C V M Copray

Survival and Functionality of Human Induced Pluripotent Stem Cell-Derived Oligodendrocytes in a Nonhuman Primate Model for Multiple Sclerosis

人类诱导性多能干细胞衍生的少突胶质细胞在非人类灵长类动物多发性硬化症模型中的存活和功能

Arun Thiruvalluvan, Marcin Czepiel, Yolanda A Kap, Ietje Mantingh-Otter, Ilia Vainchtein, Jeroen Kuipers, Marjolein Bijlard, Wia Baron, Ben Giepmans, Wolfgang Brück, Bert A 't Hart, Erik Boddeke, Sjef Copray

Comparison of Human Primary with Human iPS Cell-Derived Dopaminergic Neuron Grafts in the Rat Model for Parkinson's Disease

在帕金森病大鼠模型中,比较人原代多巴胺能神经元移植与人诱导多能干细胞来源的多巴胺能神经元移植的效果

Peng, Su-Ping; Copray, Sjef

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9

血清诱导的胶质母细胞瘤神经球分化导致迁移/侵袭能力增强,这与 MMP9 增加有关

Justin V Joseph, Ingrid A M van Roosmalen, Ellen Busschers, Tushar Tomar, Siobhan Conroy, Ellie Eggens-Meijer, Natalia Peñaranda Fajardo, Milind M Pore, Veerakumar Balasubramanyian, Michiel Wagemakers, Sjef Copray, Wilfred F A den Dunnen, Frank A E Kruyt

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion

TGF-β 是胶质母细胞瘤中 ZEB1 依赖性间充质转分化的诱导剂,与肿瘤侵袭有关

J V Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, A M E Walenkamp, E Boddeke, V Balasubramanyian, M Wagemakers, W F A den Dunnen, F A E Kruyt

Overexpression of polysialylated neural cell adhesion molecule improves the migration capacity of induced pluripotent stem cell-derived oligodendrocyte precursors

聚唾液酸化神经细胞粘附分子的过度表达提高了诱导多能干细胞衍生的少突胶质细胞前体的迁移能力

Marcin Czepiel, Lasse Leicher, Katja Becker, Erik Boddeke, Sjef Copray

Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons

对iPSC衍生的中脑-间脑多巴胺能神经元的遗传和表观遗传特征进行详细分析

Roessler, Reinhard; Smallwood, Sebastien A; Veenvliet, Jesse V; Pechlivanoglou, Petros; Peng, Su-Ping; Chakrabarty, Koushik; Groot-Koerkamp, Marian J A; Pasterkamp, R Jeroen; Wesseling, Evelyn; Kelsey, Gavin; Boddeke, Erik; Smidt, Marten P; Copray, Sjef

Apocynin, a low molecular oral treatment for neurodegenerative disease

阿朴西宁,一种用于治疗神经退行性疾病的小分子口服药物

't Hart, Bert A; Copray, Sjef; Philippens, Ingrid

Induced pluripotent stem cell technology and direct conversion: new possibilities to study and treat Parkinson's disease

诱导多能干细胞技术及其直接转化:帕金森病研究和治疗的新机遇

Roessler, Reinhard; Boddeke, Erik; Copray, Sjef