日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCT

移植前靶向TNFRSF25和CD25可刺激受体靶组织中的调节性T细胞(Tregs),从而减轻造血干细胞移植后的移植物抗宿主病(GVHD)。

McManus, Duneia; Copsel, Sabrina N; Pfeiffer, Brent J; Wolf, Dietlinde; Barreras, Henry; Ma, Symon; Khodor, Ali; Komai, Seitaro; Burgos da Silva, Marina; Hazime, Hajar; Gallardo, Miguel; Lime, Sarah Grace; van den Brink, Marcel R M; Park, Jung-Hyun; Abreu, Maria T; Hill, Geoffrey R; Perez, Victor L; Levy, Robert B

BLIMP-1 and CEACAM1 cooperatively regulate human Treg homeostasis and function to control xenogeneic GVHD

BLIMP-1 和 CEACAM1 协同调节人 Treg 细胞稳态,并发挥控制异种移植物抗宿主病 (GVHD) 的功能。

Ying Ding ,Aixin Yu ,Milos Vujanac ,Sabrina N Copsel ,Alejandro Moro ,Luis Nivelo ,Molly Dalzell ,Nicolas Tchitchek ,Michelle Rosenzwajg ,Alejandro V Villarino ,Robert B Levy ,David Klatzmann ,Thomas R Malek

Generation of SLA-DQ Knockout Pigs and Screening for Anti-SLA-DQ Antibodies in Sera From Naïve and HLA Class II-sensitized Patients.

构建 SLA-DQ 基因敲除猪,并筛选未感染和 HLA II 类致敏患者血清中的抗 SLA-DQ 抗体

Estrada Jose L, Reyes Luz M, Wang Zhang Yu, Burlak Chris, Gennuso Victor Novara, Figueroa Ovidio, Levkovitz Coral, Vianna Rodrigo M, Copsel Sabrina, Tector Matt, Tector A Joseph

Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT

移植前靶向TNFRSF25和CD25可刺激受体靶组织中的调节性T细胞(Tregs),从而减轻造血干细胞移植后的移植物抗宿主病(GVHD)。

McManus, Duneia; Copsel, Sabrina N; Pffeifer, Brent J; Wolf, Dietlinde; Barreras, Henry; Ma, Symon; Khodor, Ali; Komai, Seitaro; Burgos da Silva, Marina; Hazime, Hajar; Gallardo, Miguel; van den Brink, Marcel Rm; Abreu, Maria T; Hill, Geoffrey R; Perez, Victor L; Levy, Robert B

Minnelide suppresses GVHD and enhances survival while maintaining GVT responses

Minnelide 可抑制 GVHD 并提高存活率,同时维持 GVT 反应。

Copsel, Sabrina N; Garrido, Vanessa T; Barreras, Henry; Bader, Cameron S; Pfeiffer, Brent; Mateo-Victoriano, Beatriz; Wolf, Dietlinde; Gallardo, Miguel; Paczesny, Sophie; Komanduri, Krishna V; Benjamin, Cara L; Villarino, Alejandro V; Saluja, Ashok K; Levy, Robert B

Regulatory T Cell Amelioration of Graft-versus-Host Disease following Allogeneic/Xenogeneic Hematopoietic Stem Cell Transplantation Using Mobilized Mouse and Human Peripheral Blood Donors

使用动员的小鼠和人类外周血供体进行同种异体/异种造血干细胞移植后调节性 T 细胞改善移植物抗宿主病

Henry Barreras, Sabrina N Copsel, Cameron S Bader, Ying Ding, Dietlinde Wolf, Charles Cash, Caleb J Stacey, Cara Benjamin, Mathew M Seavey, Jeffrey Wolf, Rahul R Jasuja, Brent Pfeiffer, Geoffrey R Hill, Krishna V Komanduri, Roland Jurecic, Thomas R Malek, Robert B Levy

Recipient Tregs: Can They Be Exploited for Successful Hematopoietic Stem Cell Transplant Outcomes?

受体调节性T细胞:能否利用它们来提高造血干细胞移植的成功率?

Copsel, Sabrina N; Wolf, Dietlinde; Pfeiffer, Brent; Barreras, Henry; Perez, Victor L; Levy, Robert B

Improved NK Cell Recovery Following Use of PTCy or Treg Expanded Donors in Experimental MHC-Matched Allogeneic HSCT

在实验性MHC匹配的异基因造血干细胞移植中,使用PTCy或扩增的Treg供体后NK细胞恢复得到改善。

Wolf, Dietlinde; Barreras, Henry; Copsel, Sabrina N; Komanduri, Krishna V; Levy, Robert B

Use of Post-transplant Cyclophosphamide Treatment to Build a Tolerance Platform to Prevent Liquid and Solid Organ Allograft Rejection

利用移植后环磷酰胺治疗建立耐受平台以预防液体和实体器官同种异体移植排斥反应

Lightbourn, Casey O; Wolf, Dietlinde; Copsel, Sabrina N; Wang, Ying; Pfeiffer, Brent J; Barreras, Henry; Bader, Cameron S; Komanduri, Krishna V; Perez, Victor L; Levy, Robert B

STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets

STING 差异调节由 CD8 和 CD4 T 细胞亚群介导的实验性 GVHD

Cameron S Bader, Henry Barreras, Casey O Lightbourn, Sabrina N Copsel, Dietlinde Wolf, Jingjing Meng, Jeonghyun Ahn, Krishna V Komanduri, Bruce R Blazar, Lei Jin, Glen N Barber, Sabita Roy, Robert B Levy