日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel gold(I) complexes induce apoptosis in leukemia cells via the ROS-induced mitochondrial pathway with an upregulation of Harakiri and overcome multi drug resistances in leukemia and lymphoma cells and sensitize drug resistant tumor cells to apoptosis in vitro

新型金(I)复合物通过 ROS 诱导的线粒体通路诱导白血病细胞凋亡,上调 Harakiri 水平,克服白血病和淋巴瘤细胞的多种药物耐药性,并使耐药肿瘤细胞对体外凋亡敏感

Marie-C Ahrweiler-Sawaryn, Animesh Biswas, Corazon Frias, Jerico Frias, Nicola L Wilke, Nathalie Wilke, Albrecht Berkessel, Aram Prokop

Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro

二羟基喹啉酮通过线粒体途径以 Bcl-2 和 Caspase-3 依赖的方式诱导白血病和淋巴瘤细胞凋亡,并克服体外对细胞抑制药物的耐药性

Jennifer Baas, Sebastian Bieringer, Corazon Frias, Jerico Frias, Carolina Soehnchen, Corinna Urmann, Steffi Ritter, Herbert Riepl, Aram Prokop

B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner

B-去甲亚甲基秋水仙碱 PT-100 通过内在途径以 Caspase 非依赖的方式选择性诱导多药耐药人类癌细胞凋亡

Andreas Stein, Persefoni Hilken Née Thomopoulou, Corazon Frias, Sina M Hopff, Paloma Varela, Nicola Wilke, Arul Mariappan, Jörg-Martin Neudörfl, Alexey Yu Fedorov, Jay Gopalakrishnan, Benoît Gigant, Aram Prokop, Hans-Günther Schmalz

A metal-free salalen ligand with anti-tumor and synergistic activity in resistant leukemia and solid tumor cells via mitochondrial pathway

一种通过线粒体途径在耐药性白血病和实体瘤细胞中具有抗肿瘤和协同活性的无金属salalen配体

Sina M Hopff, Qifang Wang, Corazon Frias, Marie Ahrweiler, Nicola Wilke, Nathalie Wilke, Albrecht Berkessel, Aram Prokop