Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex
Ku介导的末端连接失活可通过耗竭核糖核苷酸还原酶抑制剂Sml1来抑制mec1Δ致死性,该过程由Tel1激酶和Mre11复合物控制。
期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.25.23.10652-10664.2005
Corda, Yves; Lee, Sang Eun; Guillot, Sylvine; Walther, André; Sollier, Julie; Arbel-Eden, Ayelet; Haber, James E; Géli, Vincent