日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities.

表观遗传和转录程序决定骨肉瘤亚型并建立可靶向的脆弱性。

López-Fuentes Eunice, Clugston Andrew S, Lee Alex G, Sayles Leanne C, Sorensen Natalie, Pons Ventura Maria V, Leung Stanley G, Dinh Truc, Breese Marcus R, Sweet-Cordero E Alejandro

Tabular foundation model predicts alternative lengthening of telomeres (ALT) and identifies SMARCAL1 as a target in ALT-driven cancers

表格基础模型预测端粒替代延长(ALT),并将SMARCAL1确定为ALT驱动型癌症的靶点

Bennett, D; Wierdl, M; Chakraborty, S; Johnson, J D; Akingbehin, V; Estevez-Prado, D; Feng, Y; Morsby, J J; Harper, J; Mohammad Nezhady, M A; Pan, M; Ocasio-Martinez, N; Catlett, J L; Nations, T B; Dharia, N V; Robichaud, A; Herman, A; Zhang, S; Kelly, J; Steele, J; Rusch, M; Wienand, K; Campbell, C D; Alexe, G; Vazquez, F; Getz, G; Roberts, Cwm; Mullighan, C G; Sweet-Cordero, E A; Reynolds, C P; Koneru, B; Shelat, A A; Durbin, A D; Bernstein, E; Ma, X; Stegmaier, K; Geeleher, P; Guenther, L M

Consistently processed RNA sequencing data from 50 sources enriched for pediatric data

一致处理的来自 50 个来源的 RNA 测序数据,其中儿科数据尤为丰富。

Beale, Holly C; Learned, Katrina; Kephart, Ellen T; Lyle, A Geoffrey; van den Bout, Anouk; McCabe, Molly; Echandia-Monroe, Kathryn; Khare, Mansi J; Huang, Elise Y; Jariwala, Sneha; Antilla, Reyna; Cheney, Allison; Lee, Alex G; Sayles, Leanne C; Leung, Stanley G; Vasquez, Yvonne A; Sanders, Lauren; Haussler, David; Salama, Sofie R; Sweet-Cordero, E Alejandro; Vaske, Olena M

56: NPRL2 loss enhances DNA damage while isolating cGAS-STING pathway and conferring immunotherapy resistance

56:NPRL2 缺失会加剧 DNA 损伤,同时隔离 cGAS-STING 通路并赋予免疫治疗耐药性。

Young, Elizabeth P; Johnson, Christine A; Lee, Alex G; Morris, Douglass; Tsui, Jessica; Breese, Marcus R; Camara Serrano, Juan Antonio; Schott, Courtney R; Abram, Clare L; Leung, Stanley G; Sayles, Leanne C; Pettiwala, Aafrin M; Gutierrez Vera, Vanessa S; Lowell, Clifford A; Combes, Alexis J; McEachron, Troy A; Sweet-Cordero, E Alejandro; Liu, Xiande; Onel, Muhammed; He, Hongchao; Zhang, Xuesong; Zhang, Yanting; Hoang, Anh; Peng, Guang; Jonasch, Eric

Collaborating across sectors in service of open science, precision oncology, and patients: an overview of the AACR Project GENIE (Genomics Evidence Neoplasia Information Exchange) Biopharma Collaborative (BPC)

跨部门合作,服务于开放科学、精准肿瘤学和患者:AACR 项目 GENIE(基因组学证据肿瘤信息交换)生物制药合作组织 (BPC) 概述

Acebedo, A; Bedard, P L; Brown, S; Ceca, E; Fiandalo, M; Fuchs, H; Guo, X; Hoppe, J N; Kehl, K L; Kundra, R; Lavery, J A; LeNoue-Newton, M L; Lepisto, E; Mastrogiacomo, B; Micheel, C M; Nayan, C; Newcomb, A; Nichols, C; Panageas, K S; Piening, B; Pillai, S; Postle, A; Potter, R; Riely, G J; Rizvi, H; Rudolph, J; Schrag, D; Sweeney, S M; Sweet-Cordero, E A; Turski, M; Wingord, E; Wu, T J; Yu, T; Yu, C

Osteosarcoma through the Lens of Bone Development, Signaling, and Microenvironment

从骨发育、信号传导和微环境的角度看骨肉瘤

Young, Elizabeth P; Marinoff, Amanda E; Lopez-Fuentes, Eunice; Sweet-Cordero, E Alejandro

Pre-and post-HSCT use of TKI therapy for fusion-driven B-ALL: A case series of five pediatric, adolescent and young adult patients

融合驱动型B细胞急性淋巴细胞白血病(B-ALL)患者在造血干细胞移植(HSCT)前后应用酪氨酸激酶抑制剂(TKI)治疗:5例儿童、青少年和青年患者的病例系列研究

Shumock, Savannah S; Temple, William C; Marinoff, Amanda; Aaronson, Kathryn; Southworth, Erica; Xirenayi, Simayijiang; Lee, Alex G; Leung, Stanley G; Sweet-Cordero, E Alejandro; Hermiston, Michelle; Higham, Christine; Stieglitz, Elliot

Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies

更昔洛韦诱导的突变存在于多种移植后恶性肿瘤中。

Fang, Hu; Yan, Helen H N; Bilardi, Rebecca A; Flensburg, Christoffer; Yang, Haocheng; Barbour, Jayne A; Siu, Hoi Cheong; Turski, Michelle; Chew, Edward; Xu, Zhen; Lam, Siu T; Sharma, Rakesh; Xu, Mengya; Li, Junshi; Ip, Ho W; Cheung, Carol Y M; Huen, Michael S Y; Sweet-Cordero, E Alejandro; Majewski, Ian J; Leung, Suet Y; Wong, Jason W H

Synthetic Vulnerabilities in the KRAS Pathway

KRAS通路中的合成脆弱性

Roman, Marta; Hwang, Elizabeth; Sweet-Cordero, E Alejandro

Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses

用于癌症网络分析的癌蛋白特异性分子相互作用图谱(SigMaps)

Broyde, Joshua; Simpson, David R; Murray, Diana; Paull, Evan O; Chu, Brennan W; Tagore, Somnath; Jones, Sunny J; Griffin, Aaron T; Giorgi, Federico M; Lachmann, Alexander; Jackson, Peter; Sweet-Cordero, E Alejandro; Honig, Barry; Califano, Andrea