日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural analyses and substrate profiling of PPEP-3 provide new insights into the molecular basis of Pro-Pro endopeptidase specificity

PPEP-3的结构分析和底物谱分析为Pro-Pro内肽酶特异性的分子基础提供了新的见解

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114360
Claushuis, Bart; Wojtalla, Fabian; Papenhagen, Lisa; Cordfunke, Robert A; de Ru, Arnoud H; van Leeuwen, Hans C; Corver, Jeroen; Hensbergen, Paul J; Baumann, Ulrich
发表日期：2026
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Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs.

用等位基因选择性siRNA治疗后，体内血管性血友病2B型表型得到改善

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2024014601
Linthorst Noa A, Jongejan Yvonne K, Dirven Richard J, Laan Sebastiaan N J, Bierings Ruben, Casari Caterina, Cordfunke Robert A, Dahlman James E, Dolezal Natasja, Drijfhout Jan Wouter, Leebeek Frank W G, Ruhaak L Renee, Schrader Echeverri Elisa, Voorberg Jan, van Vlijmen Bart J M, Denis Cécile V, Eikenboom Jeroen C J
心血管
发表日期：2025
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Branched tetrameric lactoferricin peptides modified with diaminopropionic acid exhibit potent antimicrobial and wound-healing activities

经二氨基丙酸修饰的支链四聚乳铁蛋白肽表现出强大的抗菌和伤口愈合活性

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1719557
Vavilthota, Nikitha; Babuççu, Gizem; Cordfunke, Robert A; de Boer, Leonie; Balraadjsing, Payal; Boekema, Bouke K H L; Drijfhout, Jan W; Riool, Martijn; Zaat, Sebastian A J
发表日期：2025
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Machine Learning-Identified Potent Antimicrobial Peptides Against Multidrug-Resistant Bacteria and Skin Infections

利用机器学习鉴定出对抗多重耐药菌和皮肤感染的强效抗菌肽

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics14111172
Babuççu, Gizem; Vavilthota, Nikitha; Bournez, Colin; de Boer, Leonie; Cordfunke, Robert A; Nibbering, Peter H; van Westen, Gerard J P; Drijfhout, Jan W; Zaat, Sebastian A J; Riool, Martijn
炎症/感染
发表日期：2025
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SAAP-148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core

SAAP-148 低聚形成六聚体，构成疏水性内核。

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202500112
Hodzic, Aden; Vejzovic, Djenana; Topciu, Altea; Kuhlmann, Kirill; Kumar, Raj; Mroginski, Maria Andrea; de Miguel, Alejandra; Hofmann, Pia; Zangger, Klaus; Weingarth, Markus; Cordfunke, Robert A; Drijfhout, Jan W; Nibbering, Peter; Belicka, Michal; Lohner, Karl; Malanovic, Nermina
发表日期：2025
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In-Depth Specificity Profiling of Endopeptidases Using Dedicated Mix-and-Split Synthetic Peptide Libraries and Mass Spectrometry

利用专用混合-裂解合成肽库和质谱技术对内肽酶进行深入的特异性分析

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.3c01215
Claushuis, Bart; Cordfunke, Robert A; de Ru, Arnoud H; Otte, Annemarie; van Leeuwen, Hans C; Klychnikov, Oleg I; van Veelen, Peter A; Corver, Jeroen; Drijfhout, Jan W; Hensbergen, Paul J
发表日期：2023
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Bactericidal Activity to Escherichia coli: Different Modes of Action of Two 24-Mer Peptides SAAP-148 and OP-145, Both Derived from Human Cathelicidine LL-37

两种源自人抗菌肽 LL-37 的 24 肽 SAAP-148 和 OP-145 对大肠杆菌的杀菌活性：不同的作用机制

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics12071163
Ön, Ayse; Vejzovic, Djenana; Jennings, James; Parigger, Lena; Cordfunke, Robert A; Drijfhout, Jan Wouter; Lohner, Karl; Malanovic, Nermina
Human
发表日期：2023
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Novel Antibacterial Agents SAAP-148 and Halicin Combat Gram-Negative Bacteria Colonizing Catheters

新型抗菌剂 SAAP-148 和 Halicin 可对抗定植于导管的革兰氏阴性菌

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics12121743
Bouhrour, Nesrine; van der Reijden, Tanny J K; Voet, Michella M; Schonkeren-Ravensbergen, Bep; Cordfunke, Robert A; Drijfhout, Jan Wouter; Bendali, Farida; Nibbering, Peter H
微生物学
发表日期：2023
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CalcAMP: A New Machine Learning Model for the Accurate Prediction of Antimicrobial Activity of Peptides

CalcAMP：一种用于精确预测肽类抗菌活性的新型机器学习模型

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics12040725
Bournez, Colin; Riool, Martijn; de Boer, Leonie; Cordfunke, Robert A; de Best, Leonie; van Leeuwen, Remko; Drijfhout, Jan Wouter; Zaat, Sebastian A J; van Westen, Gerard J P
GPCR/Calcium/cAMP
发表日期：2023
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Where Electrostatics Matter: Bacterial Surface Neutralization and Membrane Disruption by Antimicrobial Peptides SAAP-148 and OP-145

静电作用至关重要：抗菌肽 SAAP-148 和 OP-145 对细菌表面的中和作用和对细胞膜的破坏作用

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom12091252
Vejzovic, Djenana; Piller, Paulina; Cordfunke, Robert A; Drijfhout, Jan W; Eisenberg, Tobias; Lohner, Karl; Malanovic, Nermina
微生物学
细胞生物学
发表日期：2022
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