日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models

ABE9 与 SpRY Cas9 切口酶融合,可实现精确构建无旁观者效应的小鼠模型。

Ong, Jun Kai; Bhunia, Sayari; Hilbert, Beate; Kirschner, Vanessa; Duglosz, Sascha; Zimmermann, Frank; Freichel, Marc; Cornean, Alex

Streamlined Generation of CRISPR/Cas9-Mediated Single-Cell Knockout Clones in Murine Cell Lines.

简化小鼠细胞系中 CRISPR/Cas9 介导的单细胞敲除克隆的生成

Hub Tobias, Cornean Alex, Round Kellen, Fleming Thomas, Freichel Marc, Medert Rebekka

CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease

基于 CRISPR 的基因敲除和碱基编辑证实了 MYRF 在心脏发育和先天性心脏病中的作用

Doering, Lino; Cornean, Alex; Thumberger, Thomas; Benjaminsen, Joergen; Wittbrodt, Beate; Kellner, Tanja; Hammouda, Omar T; Gorenflo, Matthias; Wittbrodt, Joachim; Gierten, Jakob

Positively charged residues at the channel mouth boost single-file water flow

通道口处的带正电荷的残留物促进单列水流

Horner, Andreas; Siligan, Christine; Cornean, Alex; Pohl, Peter