日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deciphering key parameters enhancing lentiviral vector producer cells yields: Vector components copy number and expression

解析提高慢病毒载体生产细胞产量的关键参数:载体组分拷贝数和表达

Formas-Oliveira, Ana S; Ferreira, Mariana Valentim; Coroadinha, Ana Sofia

SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production

利用SLC20A1基因敲除稳定表达融合性长臂猿白血病病毒包膜糖蛋白,用于慢病毒载体的生产

Nogueira, Rodrigo José; Rodrigues, Ana Filipa; Mestre, Daniel Alexandre; Coroadinha, Ana Sofia

3D co-cultures of primary human hepatocytes and Kupffer-like cells to address innate immune responses to rAAV.

利用原代人肝细胞和库普弗样细胞的 3D 共培养来研究对 rAAV 的先天免疫反应。

Ramella Gal Isabella, Arez Francisca, Correia Inês P, Domenici Giacomo, Fernandes Sofia, Silva Gabriela, Saldanha Inês, Duarte Nadia, Freitas Catarina, Alves Paula M, Maier Udo, Coroadinha Ana Sofia, du Plessis François, Brito Catarina

Host Cell Restriction Factors Blocking Efficient Vector Transduction: Challenges in Lentiviral and Adeno-Associated Vector Based Gene Therapies

宿主细胞限制因子阻碍高效载体转导:慢病毒和腺相关载体基因治疗面临的挑战

Coroadinha, Ana Sofia

Extending AAV Packaging Cargo through Dual Co-Transduction: Efficient Protein Trans-Splicing at Low Vector Doses

通过双重共转导延长AAV包装载荷:低载体剂量下的高效蛋白质反式剪接

Ferreira, Mariana V; Fernandes, Sofia; Almeida, Ana Isabel; Neto, Salomé; Mendes, João P; Silva, Ricardo J S; Peixoto, Cristina; Coroadinha, Ana Sofia

Evaluation of Structurally Distorted Split GFP Fluorescent Sensors for Cell-Based Detection of Viral Proteolytic Activity

评估结构畸变分裂型GFP荧光传感器在基于细胞的病毒蛋白水解活性检测中的应用

Guerreiro, Miguel R; Fernandes, Ana R; Coroadinha, Ana S

Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes

改良的GaLV-TR糖蛋白用于构建假型慢病毒载体:病毒蛋白酶活性对慢病毒假型生产的影响

Tomás, Hélio A; Mestre, Daniel A; Rodrigues, Ana F; Guerreiro, Miguel R; Carrondo, Manuel J T; Coroadinha, Ana Sofia

Pseudotyping retrovirus like particles vaccine candidates with Hepatitis C virus envelope protein E2 requires the cellular expression of CD81

利用丙型肝炎病毒包膜蛋白E2构建的假型逆转录病毒样颗粒疫苗候选物需要细胞表达CD81。

Soares, Hugo R; Castro, Rute; Tomás, Hélio A; Carrondo, Manuel J T; Alves, Paula M; Coroadinha, Ana S

Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins

塞姆利基森林病毒复制子颗粒在无血清培养基 BHK-21 细胞培养中的生产及其用于表达不同蛋白质的用途

Sandra Fernanda Suárez-Patiño, Thaissa Consoni Bernardino, Eutimio Gustavo Fernández Núñez, Renato Mancini Astray, Carlos Augusto Pereira, Hugo R Soares, Ana S Coroadinha, Soraia Attie Calil Jorge

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1

MicroRNA-146a 通过靶向 NOD1 来控制 γδT 细胞的功能可塑性

Nina Schmolka, Pedro H Papotto, Paula Vargas Romero, Tiago Amado, Francisco J Enguita, Ana Amorim, Ana F Rodrigues, Katrina E Gordon, Ana S Coroadinha, Mark Boldin, Karine Serre, Amy H Buck, Anita Q Gomes, Bruno Silva-Santos