日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies.

纳米抗体对α7尼古丁乙酰胆碱受体负变构调节的发现和机制。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2514734123
Barilone Nathalie, Vangelatou Maria, Marouf F Zahra, Dejean de la Bâtie Gabrielle, Li Qimeng, Lafaye Pierre, Aymé Gabriel, Corringer Pierre-Jean, Prevost Marie S
表观遗传
发表日期：2026
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The interpeduncular nucleus blunts the rewarding effect of nicotine.

脚间核减弱了尼古丁的奖赏效应

期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2025.03.035
Jehl Joachim, Ciscato Maria, Vicq Eléonore, Guyon Nicolas, Dejean de la Batie Gabrielle, Mondoloni Sarah, Frangieh Jacinthe, Mohayyaei Monir, Nguyen Claire, Pons Stéphanie, Maskos Uwe, Hardelin Jean-Pierre, Marti Fabio, Corringer Pierre-Jean, Faure Philippe, Mourot Alexandre
发表日期：2025
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Mapping the molecular motions of 5-HT(3) serotonin-gated channel by voltage-clamp fluorometry

利用电压钳荧光法绘制5-HT(3)血清素门控通道的分子运动图谱

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.93174
Peverini, Laurie; Shi, Sophie; Medjebeur, Karima; Corringer, Pierre-Jean
IF
5-HT
发表日期：2024
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Short-chain mono-carboxylates as negative modulators of allosteric transitions in Gloeobacter violaceus ligand-gated ion channel, and impact of a pre-β5 strand (Loop Ω) double mutation on crotonate, not butyrate effect

短链单羧酸盐作为紫球杆菌配体门控离子通道变构转变的负调控剂，以及前β5链（Ω环）双突变对巴豆酸而非丁酸的影响

期刊:Physiological Reports
影响因子:1.9
doi:10.14814/phy2.15916
Van Renterghem, Catherine; Nemecz, Ákos; Medjebeur, Karima; Corringer, Pierre-Jean
信号转导
发表日期：2024
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Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor

生成可作为α7尼古丁乙酰胆碱受体的沉默正向变构调节剂的纳米抗体

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-023-04779-8
Li, Qimeng; Nemecz, Ákos; Aymé, Gabriel; Dejean de la Bâtie, Gabrielle; Prevost, Marie S; Pons, Stéphanie; Barilone, Nathalie; Baachaoui, Rayen; Maskos, Uwe; Lafaye, Pierre; Corringer, Pierre-Jean
信号转导
发表日期：2023
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Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway

甘氨酸受体胞外结构域的侧向窗孔是氯离子主要渗透途径的组成部分。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adc9340
Cerdan, Adrien H; Peverini, Laurie; Changeux, Jean-Pierre; Corringer, Pierre-Jean; Cecchini, Marco
信号转导
发表日期：2022
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Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors

利用串联体重新研究α5在α4β2尼古丁受体中的作用

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-020-03558-z
Prevost, Marie S; Bouchenaki, Hichem; Barilone, Nathalie; Gielen, Marc; Corringer, Pierre-Jean
信号转导
发表日期：2021
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Conformational transitions of the serotonin 5-HT(3) receptor

血清素5-HT(3)受体的构象转变

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-018-0672-3
Polovinkin, Lucie; Hassaine, Ghérici; Perot, Jonathan; Neumann, Emmanuelle; Jensen, Anders A; Lefebvre, Solène N; Corringer, Pierre-Jean; Neyton, Jacques; Chipot, Christophe; Dehez, Francois; Schoehn, Guy; Nury, Hugues
信号转导
5-HT
发表日期：2018
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Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation

由碱性pH值调控的五聚体离子通道的晶体结构显示出一个完全开放的孔道，并确定了一个用于调节的腔体。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1717700115
Hu, Haidai; Nemecz, Ákos; Van Renterghem, Catherine; Fourati, Zaineb; Sauguet, Ludovic; Corringer, Pierre-Jean; Delarue, Marc
信号转导
发表日期：2018
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The dual-gate model for pentameric ligand-gated ion channels activation and desensitization

五聚体配体门控离子通道激活和脱敏的双门模型

期刊:Journal of Physiology-London
影响因子:4.4
doi:10.1113/JP275100
Gielen, Marc; Corringer, Pierre-Jean
发表日期：2018
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