Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
溶酶体蛋白水解和自噬需要早老素 1,而阿尔茨海默病相关的 PS1 突变会破坏这些过程
期刊:Cell
影响因子:45.5
doi:10.1016/j.cell.2010.05.008
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak, Yasuo Uchiyama, David Westaway, Ana Maria Cuervo, Ralph A Nixon