日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

巨胞饮作用在胰腺癌代谢应激下维持 CAF 亚型特性

Yijuan Zhang ,Li Ling ,Rabi Murad ,Swetha Maganti ,Ambroise Manceau ,Hannah A Hetrick ,Madelaine Neff ,Cheska Marie Galapate ,Shea F Grenier ,Florent Carrette ,Karen Duong-Polk ,Anindya Bagchi ,David A Scott ,Yoav Altman ,Jennifer L Hope ,Andrew M Lowy ,Linda M Bradley ,Cosimo Commisso

PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer

PI5P4Kα促进葡萄糖和铁的吸收,从而维持胰腺癌的代谢功能。

Gurpreet K Arora ,Ryan M Loughran ,Kyanh Ly ,Cheska Marie Galapate ,Alicia Llorente ,Taylor R Anderson ,Cynthia Y Zhang ,Shea F Grenier ,Li Ling ,Sophia Crabtree ,Guillem Lambies ,Chantal Pauli ,David A Scott ,Yoav Altman ,Benji Portillo ,Rabi Murad ,Cosimo Commisso ,Brooke M Emerling

Glutamine mimicry suppresses tumor progression through asparagine metabolism in pancreatic ductal adenocarcinoma

谷氨酰胺模拟通过天冬酰胺代谢抑制胰腺导管腺癌的肿瘤进展

Maria Victoria Recouvreux, Shea F Grenier, Yijuan Zhang, Edgar Esparza, Guillem Lambies, Cheska Marie Galapate, Swetha Maganti, Karen Duong-Polk, Deepika Bhullar, Razia Naeem, David A Scott, Andrew M Lowy, Hervé Tiriac, Cosimo Commisso

Cell polarity proteins promote macropinocytosis in response to metabolic stress

细胞极性蛋白促进巨胞饮作用以应对代谢压力

Guillem Lambies, Szu-Wei Lee, Karen Duong-Polk, Pedro Aza-Blanc, Swetha Maganti, Cheska M Galapate, Anagha Deshpande, Aniruddha J Deshpande, David A Scott, David W Dawson, Cosimo Commisso

Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness

癌症相关成纤维细胞中的巨胞饮作用依赖于 CaMKK2/ARHGEF2 信号传导和支持肿瘤和基质细胞适应性的功能

Yijuan Zhang, M Victoria Recouvreux, Michael Jung, Koen M O Galenkamp, Yunbo Li, Olga Zagnitko, David A Scott, Andrew M Lowy, Cosimo Commisso

Golgi Acidification by NHE7 Regulates Cytosolic pH Homeostasis in Pancreatic Cancer Cells

NHE7介导的高尔基体酸化调节胰腺癌细胞胞质pH稳态

Koen M O Galenkamp,Paulina Sosicka,Michael Jung,M Victoria Recouvreux,Yijuan Zhang,Matthew R Moldenhauer,Giovanni Brandi,Hudson H Freeze,Cosimo Commisso

Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

谷氨酰胺耗竭通过调节Slug促进胰腺癌的EMT和转移

Maria Victoria Recouvreux,Matthew R Moldenhauer,Koen M O Galenkamp,Michael Jung,Brian James,Yijuan Zhang,Andrew Lowy,Anindya Bagchi,Cosimo Commisso

Rac1 and EGFR cooperate to activate Pak in response to nutrient stress

Rac1 和 EGFR 协同激活 Pak 以应对营养压力

Szu-Wei Lee, Cosimo Commisso

Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras

胰腺癌细胞中 EGFR 效应子和反馈信号的代谢调节需要 K-Ras

Szu-Wei Lee, Cosimo Commisso

EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

EGFR-Pak信号通路选择性地调节谷氨酰胺缺乏诱导的巨胞饮作用

Szu-Wei Lee,Yijuan Zhang,Michael Jung,Nathalia Cruz,Basheer Alas,Cosimo Commisso