日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

小分子抑制剂和 CRISPR/Cas9 诱变表明 SMYD2 和 SMYD3 活性对于癌细胞自主增殖而言并非必需

Michael J Thomenius, Jennifer Totman, Darren Harvey, Lorna H Mitchell, Thomas V Riera, Kat Cosmopoulos, Alexandra R Grassian, Christine Klaus, Megan Foley, Elizabeth A Admirand, Haris Jahic, Christina Majer, Tim Wigle, Suzanne L Jacques, Jodi Gureasko, Dorothy Brach, Trupti Lingaraj, Kip West, Sherr

Initial testing (stage 1) of tazemetostat (EPZ-6438), a novel EZH2 inhibitor, by the Pediatric Preclinical Testing Program

儿科临床前测试计划对新型 EZH2 抑制剂他泽司他 (EPZ-6438) 进行初步测试(第 1 阶段)

Raushan T Kurmasheva, Melissa Sammons, Edward Favours, Jianwrong Wu, Dias Kurmashev, Katherine Cosmopoulos, Heike Keilhack, Christine R Klaus, Peter J Houghton, Malcolm A Smith

Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways

Nedd8 活化酶抑制剂 MLN4924 通过与 ATR、BRCA1/BRCA2 和染色质动力学通路相互作用,与丝裂霉素 C 产生协同作用

Khristofer Garcia, Jonathan L Blank, David C Bouck, Xiaozhen J Liu, Darshan S Sappal, Greg Hather, Katherine Cosmopoulos, Michael P Thomas, Mike Kuranda, Michael D Pickard, Ray Liu, Syamala Bandi, Peter G Smith, Eric S Lightcap

Functional delivery of viral miRNAs via exosomes

通过外泌体进行病毒 miRNA 的功能性传递

D Michiel Pegtel, Katherine Cosmopoulos, David A Thorley-Lawson, Monique A J van Eijndhoven, Erik S Hopmans, Jelle L Lindenberg, Tanja D de Gruijl, Thomas Würdinger, Jaap M Middeldorp

Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma

鼻咽癌中 Epstein-Barr 病毒 microRNA 的全面分析

Cosmopoulos, Katherine; Pegtel, Michiel; Hawkins, Jared; Moffett, Howell; Novina, Carl; Middeldorp, Jaap; Thorley-Lawson, David A