Costakis相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle

癌细胞周期的异质性决定了药物 CDK2 抑制的敏感性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56674-4

Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M Rubin, Costakis Frangou, Karen McLean, Agnieszka K Witkiewicz, Erik S Knudsen

细胞生物学

发表日期：2025

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The Extracellular Niche and Tumor Microenvironment Enhance KRAS Inhibitor Efficacy in Pancreatic Cancer

细胞外微环境和肿瘤微环境增强 KRAS 抑制剂对胰腺癌的疗效

期刊:Cancer Research

影响因子:12.5

doi:10.1158/0008-5472.CAN-23-2504

Vishnu Kumarasamy, Jianxin Wang, Costakis Frangou, Yin Wan, Andrew Dynka, Hanna Rosenheck, Prasenjit Dey, Ethan V Abel, Erik S Knudsen, Agnieszka K Witkiewicz

发表日期：2024

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Unraveling the Dynamics of Omicron (BA.1, BA.2, and BA.5) Waves and Emergence of the Deltacton Variant: Genomic Epidemiology of the SARS-CoV-2 Epidemic in Cyprus (Oct 2021-Oct 2022)

揭示 Omicron（BA.1、BA.2 和 BA.5）波的动力学和 Deltacton 变体的出现：塞浦路斯 SARS-CoV-2 流行病的基因组流行病学（2021 年 10 月 - 2022 年 10 月）

期刊:Viruses-Basel

影响因子:3.8

doi:10.3390/v15091933

Andreas C Chrysostomou, Bram Vrancken, Christos Haralambous, Maria Alexandrou, Ioanna Gregoriou, Marios Ioannides, Costakis Ioannou, Olga Kalakouta, Christos Karagiannis, Markella Marcou, Christina Masia, Michail Mendris, Panagiotis Papastergiou, Philippos C Patsalis, Despo Pieridou, Christos Shamma

发表日期：2023

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Pharmacologically targeting KRAS G12D in PDAC models: tumor cell intrinsic and extrinsic impact

在 PDAC 模型中药理学靶向 KRAS G12D：肿瘤细胞内在和外在影响

doi:10.1101/2023.03.18.533261

Vishnu Kumarasamy, Costakis Frangou, Jianxin Wang, Yin Wan, Andrew Dynka, Hanna Rosenheck, Prasenjit Dey, Ethan V Abel, Erik S Knudsen, Agnieszka K Witkiewicz

发表日期：2023

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A Comprehensive Molecular Epidemiological Analysis of SARS-CoV-2 Infection in Cyprus from April 2020 to January 2021: Evidence of a Highly Polyphyletic and Evolving Epidemic

2020年4月至2021年1月塞浦路斯SARS-CoV-2感染的综合分子流行病学分析：高度多源性和不断演变的流行病的证据

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v13061098

Chrysostomou, Andreas C; Vrancken, Bram; Koumbaris, George; Themistokleous, George; Aristokleous, Antonia; Masia, Christina; Eleftheriou, Christina; Iοannou, Costakis; Stylianou, Dora C; Ioannides, Marios; Petrou, Panagiotis; Georgiou, Vasilis; Hatziyianni, Amalia; Lemey, Philippe; Vandamme, Anne-Mieke; Patsalis, Philippos P; Kostrikis, Leondios G

发表日期：2021

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TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells

TRAIN（重复转录激活干扰素）响应哺乳动物细胞中小分子诱导的染色质不稳定

影响因子:6.4

doi:10.7554/eLife.30842

Katerina Leonova, Alfiya Safina, Elimelech Nesher, Poorva Sandlesh, Rachel Pratt, Catherine Burkhart, Brittany Lipchick, Ilya Gitlin, Costakis Frangou, Igor Koman, Jianmin Wang, Kirill Kirsanov, Marianna G Yakubovskaya, Andrei V Gudkov, Katerina Gurova

细胞生物学

发表日期：2018

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Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Predicts for Poor Patient Outcome

Sox4 表达赋予膀胱癌干细胞特性并预测患者预后不良

期刊:International Journal of Biological Sciences

影响因子:8.2

doi:10.7150/ijbs.13240

He Shen, Maxime Blijlevens, Nuo Yang, Costakis Frangou, Kayla E Wilson, Bo Xu, Yinglong Zhang, Lirui Zhang, Carl D Morrison, Lori Shepherd, Qiang Hu, Qianqian Zhu, Jianmin Wang, Song Liu, Jianmin Zhang

发育与干细胞

发表日期：2015

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A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest

一种通过抑制PTEN来改善小鼠心脏骤停后代谢复苏和存活率的新型药理学策略

期刊:American Journal of Physiology-Heart and Circulatory Physiology

影响因子:4.1

doi:10.1152/ajpheart.00748.2014

Li, Jing; Wang, Huashan; Zhong, Qiang; Zhu, Xiangdong; Chen, Sy-Jou; Qian, Yuanyu; Costakis, Jim; Bunney, Gabrielle; Beiser, David G; Leff, Alan R; Lewandowski, E Douglas; ÓDonnell, J Michael; Vanden Hoek, Terry L

发表日期：2015

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Vascular priming enhances chemotherapeutic efficacy against head and neck cancer

血管预处理可增强化疗对头颈癌的疗效

期刊:Oral Oncology

影响因子:3.9

doi:10.1016/j.oraloncology.2013.06.011

Folaron, Margaret; Kalmuk, James; Lockwood, Jaimee; Frangou, Costakis; Vokes, Jordan; Turowski, Steven G; Merzianu, Mihai; Rigual, Nestor R; Sullivan-Nasca, Maureen; Kuriakose, Moni A; Hicks, Wesley L Jr; Singh, Anurag K; Seshadri, Mukund

发表日期：2013

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Genetic deletion of NOS3 increases lethal cardiac dysfunction following mouse cardiac arrest

NOS3基因缺失会加剧小鼠心脏骤停后的致命性心脏功能障碍

期刊:Resuscitation

影响因子:4.6

doi:10.1016/j.resuscitation.2010.08.038

Beiser, David G; Orbelyan, Gerasim A; Inouye, Brendan T; Costakis, James G; Hamann, Kimm J; McNally, Elizabeth M; Vanden Hoek, Terry L

发表日期：2011

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