Costas-Insua相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models

恢复海马GABA能神经元中CB1受体的功能可以挽救亨廷顿病模型中的记忆缺陷。

期刊:Translational Neurodegeneration

影响因子:10.8

doi:10.1186/s40035-025-00500-w

Nadia Di Franco ，Iker Bengoetxea de Tena ，Andrea Sanchez-Ruiz，Alba Pereda-Velarde ，Ferran Enfedaque ，Candela Gónzalez-Arias，Lluis Maria Miquel Rio ，Analia Bortolozzi ，Rafael Rodriguez-Puertas ，Carlos Costas-Insua ，Laura Molina-Porcel ，Anna Vazquez-Oliver ，Andres Ozaita，Manuel Guzmán ，Gertrudis Perea，Silvia Ginés

发表日期：2025

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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls

CB1 受体与 cereblon 相互作用，导致 cereblon 缺乏导致的记忆力下降

期刊:EMBO Molecular Medicine

doi:10.1038/s44321-024-00054-w

Carlos Costas-Insua #, Alba Hermoso-López #, Estefanía Moreno #, Carlos Montero-Fernández #, Alicia Álvaro-Blázquez, Irene B Maroto, Andrea Sánchez-Ruiz, Rebeca Diez-Alarcia, Cristina Blázquez, Paula Morales, Enric I Canela, Vicent Casadó, Leyre Urigüen, Gertrudis Perea, Luigi Bellocchio, Ignacio Ro

发表日期：2024

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GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice

位于皮质纹状体末端的 GAP43 可抑制小鼠新奇诱发的多动症

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.0701-24.2024

Irene B Maroto, Carlos Costas-Insua, Carlos Montero-Fernández, Alba Hermoso-López, Margaux Lebouc, Raquel Bajo-Grañeras, Alicia Álvaro-Blázquez, Cristina Blázquez, Astrid Cannich, Giovanni Marsicano, Ricardo Martín, Jérôme Baufreton, Ignacio Rodríguez-Crespo, Luigi Bellocchio, Manuel Guzmán

发表日期：2024

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Poly-alanine-tailing is a modifier of neurodegeneration caused by Listerin mutation.

聚丙氨酸尾部修饰是李斯特林突变引起的神经退行性疾病的修饰因子

doi:10.1101/2024.08.24.608776

Hung Hao-Chih, Costas-Insua Carlos, Holbrook Sarah E, Stauffer Jennifer E, Martin Paige B, MÃ¼ller Tina A, Schroeder David G, Kigoshi-Tansho Yu, Xu Haifei, Rudolf RÃ¼diger, Cox Gregory A, Joazeiro Claudio A P

发表日期：2024

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Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43

大麻素受体相互作用蛋白 Gap43 控制海马循环兴奋回路

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-38026-2

Irene B Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, D

发表日期：2023

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Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10.

E3 连接酶 Pirh2 和 CRL2-KLHDC10 识别丙氨酸尾 C 降解子的机制和进化起源

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2023.113100

Patil Pratik Rajendra, Burroughs A Maxwell, Misra Mohit, Cerullo Federico, Costas-Insua Carlos, Hung Hao-Chih, Dikic Ivan, Aravind L, Joazeiro Claudio A P

免疫/内分泌

发表日期：2023

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Endocannabinoid signaling in glioma

神经胶质瘤中的内源性大麻素信号传导

影响因子:5.1

doi:10.1002/glia.24173

Costas-Insua, Carlos; Guzmán, Manuel

发表日期：2023

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The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice

GRP78-PERK 轴导致亨廷顿病 R6/1 小鼠的记忆和突触障碍

期刊:Neurobiology of Disease

影响因子:5.1

doi:10.1016/j.nbd.2023.106225

Marc Espina, Nadia Di Franco, Martina Brañas-Navarro, Irene Rodriguez Navarro, Veronica Brito, Laura Lopez-Molina, Carlos Costas-Insua, Manuel Guzmán, Silvia Ginés

发表日期：2023

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Neuronal Cannabinoid CB1 Receptors Suppress the Growth of Melanoma Brain Metastases by Inhibiting Glutamatergic Signalling

神经元大麻素 CB1 受体通过抑制谷氨酸信号传导来抑制黑色素瘤脑转移瘤的生长

doi:10.3390/cancers15092439

Carlos Costas-Insua, Marta Seijo-Vila, Cristina Blázquez, Sandra Blasco-Benito, Francisco Javier Rodríguez-Baena, Giovanni Marsicano, Eduardo Pérez-Gómez, Cristina Sánchez, Berta Sánchez-Laorden, Manuel Guzmán

发表日期：2023

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BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis.

BiP 杂合性加剧实验性肌萎缩侧索硬化症的病理恶化

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms222212533

GÃ³mez-AlmerÃa Marta, Burgaz Sonia, Costas-Insua Carlos, RodrÃguez-Cueto Carmen, Santos-GarcÃa Irene, RodrÃguez-Crespo Ignacio, GarcÃa ConcepciÃ³n, GuzmÃ¡n Manuel, de Lago Eva, FernÃ¡ndez-Ruiz Javier

发表日期：2021

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