日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Analytical strategies for identification and quantitation of heterodimers in co-formulated monoclonal antibody cocktails by native SEC-MS

利用天然尺寸排阻色谱-质谱法(SEC-MS)鉴定和定量共配制单克隆抗体混合物中的异二聚体的分析策略

Peng, Wenjing; Yan, Yuetian; Cotham, Victoria C; Heindel, Andrew; Wang, Shunhai; Li, Ning

An Online Buffer Exchange Platform for Charge Detection Mass Spectrometry Analysis of AAVs and AAV-Antibody Complexes

用于AAV和AAV-抗体复合物电荷检测质谱分析的在线缓冲液交换平台

Du, Chen; Cotham, Victoria C; Thakur, Garima; Mink, Sheldon; Tustian, Andrew D; Møller-Tank, Sven; Wang, Shunhai; Li, Ning

Development of a Novel Label-Free Subunit HILIC-MS Method for Domain-Specific Free Thiol Identification and Quantitation in Therapeutic Monoclonal Antibodies

开发一种新型的无标记亚基 HILIC-MS 方法,用于治疗性单克隆抗体中结构域特异性游离硫醇的鉴定和定量

Huang, Xiaoxiao; Wang, Xin; Cotham, Victoria C; Bramhall, David; Zhong, Jieqiang; Zhao, Yimeng; Qiu, Haibo; Wang, Shunhai; Li, Ning

Structural Motifs for CTD Kinase Specificity on RNA Polymerase II during Eukaryotic Transcription

真核转录过程中 RNA 聚合酶 II 上 CTD 激酶特异性的结构基序

Ramani, Mukesh Kumar Venkat; Escobar, Edwin E; Irani, Seema; Mayfield, Joshua E; Moreno, Rosamaria Y; Butalewicz, Jamie P; Cotham, Victoria C; Wu, Haoyi; Tadros, Meena; Brodbelt, Jennifer S; Zhang, Yan Jessie

Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains.

利用实验室对重编码细菌菌株进行进化,实现了定制硒蛋白的生产

Thyer Ross, Shroff Raghav, Klein Dustin R, d'Oelsnitz Simon, Cotham Victoria C, Byrom Michelle, Brodbelt Jennifer S, Ellington Andrew D

The GCN2-ATF4 Signaling Pathway Induces 4E-BP to Bias Translation and Boost Antimicrobial Peptide Synthesis in Response to Bacterial Infection

GCN2-ATF4信号通路诱导4E-BP,从而偏向翻译并增强抗菌肽的合成以应对细菌感染

Vasudevan, Deepika; Clark, Nicholas K; Sam, Jessica; Cotham, Victoria C; Ueberheide, Beatrix; Marr, Michael T 2nd; Ryoo, Hyung Don

Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass Spectrometry

利用紫外光解离质谱法绘制果蝇RNA聚合酶II羧基末端结构域的磷酸化模式

Mayfield, Joshua E; Robinson, Michelle R; Cotham, Victoria C; Irani, Seema; Matthews, Wendy L; Ram, Anjana; Gilmour, David S; Cannon, Joe R; Zhang, Yan Jessie; Brodbelt, Jennifer S

UVnovo: A de Novo Sequencing Algorithm Using Single Series of Fragment Ions via Chromophore Tagging and 351 nm Ultraviolet Photodissociation Mass Spectrometry

UVnovo:一种利用生色团标记和351 nm紫外光解离质谱技术,通过单系列碎片离子进行从头测序的算法

Robotham, Scott A; Horton, Andrew P; Cannon, Joe R; Cotham, Victoria C; Marcotte, Edward M; Brodbelt, Jennifer S